Monthly Archives: abril 2015

Os informamos de la organización del I Curso de Osteoporosis para Médicos Residentes organizado por la SEIOMM. El objetivo del curso es dar a conocer aspectos básicos sobre la epidemiología, diagnóstico y tratamiento de la osteoporosis en las consultas del día a día.

Estudio Dasio Resultados   GRABACIÓN de la presentación del Estudio DASIO PDF del resultado El Estudio DASIO es un estudio multicéntrico, prospectivo y observacional que se ha llevado a cabo en cerca de 300 centros de salud de atención primaria en todo el territorio español.

JAMA Intern Med. Published online April 13, 2015. doi:10.1001/jamainternmed.2015.0747. In this group of frail elderly women with osteoporosis, 1 dose of zoledronic acid improved BMD over 2 years. The clinical importance of nonsignificant increases in fracture and mortality rates in the treatment group needs further study. Since it is not known whether such therapy reduces […]

Sequential antiresorptive therapy is recommended to maintain drug increases in bone mass and support secondary mineralization of the newly formed bone. Combination therapies of antiresorptives and anabolic agents have shown a significant increase in bone mineral density compared to monotherapies. However, none of the combinations have been studied for the prevention of fractures. Combination therapy […]

The tissue-selective estrogen complex (TSEC) combines bazedoxifene and conjugated estrogens and is designed not only to improve menopausal symptoms and vulvovaginal atrophy but also to prevent bone loss. Therefore, it maintains the benefits of estrogen therapy while antagonizing the stimulation effects on the endometrium and mammary gland without the effects associated with progestins.

J Clin Endocrinol Metab. 2015 Apr;100(4):1343-9. doi: 10.1210/jc.2014-4166. Epub 2015 Feb 2. Arterialized plasma HCO3 was associated positively with cross-sectional BMD and inversely with the rate of bone loss, implying that systemic acid-base status is an important determinant of skeletal health during aging. Ongoing bone loss was linearly related to arterialized HCO3, even after adjustment […]