Could wood be a practical replacement for bone? Researchers from the National Research Council of Italy (CNR) writing in a forthcoming issue of the International Journal of Healthcare Technology and Management …

Biloine W. Young • Fri, December 21st, 2012

Could wood be a practical replacement for bone? Researchers from the National Research Council of Italy (CNR) writing in a forthcoming issue of the International Journal of Healthcare Technology and Management suggest that it can. It turns out that the structure of some woods at the microscopic level is very close to that of natural bone; both have unique biomechanical properties such as high strength and lightness.

Two researchers in Italy, Ugo Finardi (Institute for Economic Research on Firms and Growth-CERIS-CNR, and University of Torino), and Simone Sprio (Institute of Science and Technology for Ceramics – ISTEC-CNR), have carried out a case study on the implications of a new technology recently developed by the Research Group on Biomaterials of ISTEC. In that work, the researchers, Anna Tampieri, Simone Sprio and Andrea Ruffini, used a nanotechnological approach to transform rattan wood into hierarchically organized implants.

They say that these biomimetic materials have a strength and flexibility similar to natural bone, something that cannot be achieved with current metal alloy technologies. They believe that the structure of rattan wood might be used as a scaffold for creating a synthetic material to replace damaged and lost bone. An additional benefit is that such a material could be load bearing, a factor that has precluded the use of earlier biomimetic materials.

The processing of raw wood to remove chemical components incompatible with implants for humans involves heat treatment of the wood to remove cellulose, lignin and other plant materials but to leave behind a carbon skeleton that can then be infiltrated and reacted with calcium, oxygen and phosphate to make a porous material, chemically and mechanically mimicking bone.

The research team says that unlike metal alloys, ceramics and even donor bone, their patented material is low cost, has very good biomechanics, is biocompatible and can be integrated into existing bone, thus assisting in bone regeneration. The team notes that more than 2.2 million bone grafting procedures are performed annually around the world. Moreover, this number is increasing as lifestyles change and the world population experiences progressive aging. More information on this process can be found in “Human bone regeneration from wood: a novel hierarchically organized nanomaterial” in International Journal Healthcare Technology and Management, 2012, 13, 171-183.

Dr. Sprio told OTWsenior writer Elizabeth Hofheinz: “Human bones have a hierarchically organized morphology which develops over different dimensional scales, from the nano- to the macroscopic one. This feature is the key for the outstanding mechanical performances of bone and for its ability to self-repair upon limited damage. A very challenging aspect of this study was to find a way to reproduce artificially this very complex structure, since no manufacturing processes exist. It is believed that if an organized structure similar to bone in chemistry and morphology is implanted, the cells will be stimulated to form new bone with organized structure and functional.”

Seguir Leyendo Artículo

Leave a Reply

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *

  • 16 + Trece =