Densitometry and imaging techniques are currently used in clinical settings to measure bone quantity and spatial structure. Recently, Reference Point Indentation has opened the  possibility of directly assessing the mechanical characteristics of cortical bone in living individuals, adding a new dimension to the assessment of bone strength.

Bone. 2017 Feb;95:175-182. doi: 10.1016/j.bone.2016.11.003.

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Herrera S, Diez-Perez A.