In conclusion, despite the huge impact of osteoporosis worldwide, our knowledge of bone genetics and biology remains remarkably incomplete.

Our findings and models provide compelling genetic evidence of a novel molecular network regulating adult skeletal homeostasis in vivo, which may help identify new specific therapeutic targets against involution- al, inflammatory, or cancer‐induced bone wasting.

Autor: Elisa Benasciutti, Elisabetta Mariani, Laura Oliva, Maria Scolari,…

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