Secular trends in the incidence of primary hyperparathyroidism over five decades (1965–2010)

Bone 2014; 73:1-7. doi: 10.1016/j.bone.2014.12.003.

Over time, two periods of increased PHPT incidence occurred, one beginning in 1974 (121.7 per 100,000 person-years) and a second peak (86.2 per 100,000 person-years) starting in 1998. The median age of PHPT subjects has increased significantly from 55 years in 1985–1997 to 60 years of age in 1998–2010 and more patients (36%) had a parathyroidectomy in 1998–2010. A second sharp rise in PHPT incidence occurred in our community in 1998, simultaneously with the introduction of national osteoporosis screening guidelines.