BMI and the daily time spent on moderate PA were found to be correlated with femoral neck BMD in CF patients. The association between daily PA and biochemical markers of bone formation suggests that the … Leer más
LCN2 is an important catabolic adipokine in osteoblast and chondrocyte metabolism that is regulated by differentiation, inflammation and catabolic and anabolic stimuli, and LCN2 expression in chondrocytes is regulated in a paracrine manner after osteoblast … Leer más
We propose the use of AM inhibitors for the treatment of osteoporosis and other conditions leading to the loss of bone mass.
Among hip fracture patients, publication of NICE guidance and availability of generic alendronic acid was temporally associated with increased prescribing and a significant decline in subsequent fractures.
Finalizado el plazo para el envío de solicitudes para acceder a las Becas FEIOMM para la presentación de trabajos de investigación en el Congreso de la ASBMR en Atlanta, se adjunta la lista de solicitudes … Leer más
Finalizado el plazo para el envío de solicitudes para acceder a las Becas FEIOMM para la presentación de trabajos de investigación en el Congreso de la ASBMR en Atlanta, se adjunta la lista de solicitudes … Leer más
In postmenopausal women with osteoporosis previously treated with oral bisphosphonates, denosumab was associated with greater BMD increases at all measured skeletal sites and greater inhibition of bone remodeling compared with zoledronic acid.
Our data support an anti-senescence and anti-inflammatory role for the C-terminal moiety of PTHrP with potential applications in chronic inflammatory conditions such as OA.
These findings support an acceptable balance between benefit and risk with treatment with alendronate in terms of fracture outcomes, even for over 10 years of continuous use.
These results shed new light to understand adipose-tissue differentiation and physiology, increasing our knowledge about pathologies like obesity, type-2 diabetes and osteoporosis.
