A986S polymorphism of CaSR is an independent predictor of PTH level in normocalcemic hyperparathyroidism patients, but not in asymptomatic hyperparathyroidism.
In this review, we discuss the current concepts about the cellular and molecular mechanisms whereby PTHrP may induce anabolic actions in bone. Pre-clinical studies and clinical data using N-terminal PTHrP analogs are also summarized, pointing … Leer más
Calcif Tissue Int. 2015 Sep;97(3):199-200. doi: 10.1007/s00223-015-0012-7. Epub 2015 May 13. Autor: Burr DB, Allen MR.
Osteoporos Int. 2015 Sep;26(9):2223-41. doi: 10.1007/s00198-015-3149-3. Epub 2015 May 5. In this review, we summarize our current understanding of the pathophysiology of fragility fractures that occur for the first time during pregnancy and lactation, and … Leer más
PLoS One. 2015 Sep 8;10(9):e0136968. doi: 10.1371/journal.pone.0136968. eCollection 2015. Frailty and pre-frailty, in Taiwan, was closely associated with recent falls, history of hip fractures and osteoporosis among community-dwelling people 50 years of age and older. … Leer más
Osteoporos Int. 2015 Sep;26(9):2257-63. doi: 10.1007/s00198-015-3117-y. Epub 2015 Apr 10. The available data also showed that patients attending the FLSs were evaluated, treated and followed in high compliancy with the IOF standards. Some standards are … Leer más
Most of the 13 tools are feasible in clinical practice. FRAX has the largest number of externally validated and independent studies. The overall accuracy of the different tools is satisfactory (>0.70), with QFracture reaching 0.89 … Leer más
Osteoporos Int. 2015 Sep;26(9):2355-63. doi: 10.1007/s00198-015-3148-4. Epub 2015 May 6. Compared with placebo, bisphosphonates could decrease the risk of vertebral and non-vertebral fractures, reduce BSAP and CTX, and increase BMD in men with osteoporosis. Autor: … Leer más
The pharmacological management of osteoporosis in women of 50 and over in this population combines an important overuse and, to a lesser extent, underuse, although the level of inappropriateness varied strikingly depending on the CPG … Leer más
J Bone Miner Res. 2015 Sep;30(9):1551-2. doi: 10.1002/jbmr.2601. The study emphasized that remaining life expectancy is substantial: 13 years for men aged 60 years and 22 years for women aged 60 years. The substantial life … Leer más
