Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Renal Function

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These findings suggest for the first time that dabigatran has a better bone safety profile than warfarin, as warfarin treatment affects bone by reducing trabecular size and structure, increasing turnover and reducing mineralization. These differences could potentially result in a lower incidence of fractures in dabigatran treated patients

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