Here comes the sun-is vitamin D a cure for all that ails us?
J Clin Endocrinol Metab. 2015 Apr;100(4):1237-40. doi: 10.1210/jc.2015-1396 Autor: Magge SN.
Switching from tenofovir to abacavir in HIV-1-infected patients with low bone mineral density: changes in bone turnover markers and circulating sclerostin levels
The switch from tenofovir to abacavir seems to induce a positive effect on bone tissue, since bone turnover markers decreased. In addition, circulating sclerostin levels increased, a change associated with improved bone properties.
Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women
The tissue-selective estrogen complex (TSEC) combines bazedoxifene and conjugated estrogens and is designed not only to improve menopausal symptoms and vulvovaginal atrophy but also to prevent bone loss. Therefore, it maintains the benefits of estrogen … Leer más
Antiresorptives and anabolic therapy in sequence or combination for postmenopausal osteoporosis
Sequential antiresorptive therapy is recommended to maintain drug increases in bone mass and support secondary mineralization of the newly formed bone. Combination therapies of antiresorptives and anabolic agents have shown a significant increase in bone … Leer más
Bone Tissue Properties Measurement by Reference Point Indentation in Glucocorticoid-Induced Osteoporosis
Our study is the first to demonstrate that reference point indentation is sensitive enough to reflect changes in cortical bone indentation following treatment with osteoporosis therapies in patients newly exposed to glucocorticoids.
The importance of calciuria as lithogenic factors in patients with osteopenia/osteoporosis.
Patients with osteopenia/osteoporosis without lithiasis present some urinary biochemical alterations. This would explain the lack of lithogenic activity, although low calcium excretion in 24-h urine samples is a protective factor against the loss of bone … Leer más
The effects of swimming training on bone tissue in adolescence.
Although more information is needed for females, it seems that for males, swimming is associated with lower BMC and BMD.
The choice of normative pediatric reference database changes spine bone mineral density z-scores but not the relationship between bone mineral density and prevalent vertebral fractures
J Clin Endocrinol Metab. 2015 Mar;100(3):1018-27. doi: 10.1210/jc.2014-3096. Epub 2014 Dec 11. Although the use of a LSBMD Z-score threshold as part of the definition of osteoporosis in a child with VF does not appear … Leer más
Serum uric acid is associated with quantitative ultrasound parameters in men: data from the Camargo cohor
Higher serum uric acid levels in men older than 50 years are positively associated with QUS parameters. These data might suggest a better bone quality in men with elevated serum uric acid values.
A 7-year randomized, placebo-controlled trial assessing the long-term efficacy and safety of bazedoxifene in postmenopausal women with osteoporosis: effects on bone density and fracture
At 7 years, the cumulative incidences of new vertebral fractures were significantly lower in the bazedoxifene (6.4%) and bazedoxifene 20 mg (7.6%) groups than in the placebo group (9.9%); the relative risk reductions were 36.5% … Leer más
