Página 120 – SEIOMM, Sociedad Española de Investigación Ósea

Estudio Dasio Resultados

GRABACIÓN de la presentación del Estudio DASIO

El Estudio DASIO es un estudio multicéntrico, prospectivo y observacional que se ha llevado a cabo en cerca de 300 centros de salud de atención primaria en todo el territorio español.

Los objetivos del estudio han sido, en primer lugar, evaluar de la adherencia a las recomendaciones del profesional sanitario en mujeres osteoporóticos y la influencia de la incorporación de un lácteo fermentado enriquecido con calcio y vitamina D en la alimentación diaria sobre esta adherencia. Como objetivo secundario se fijo el evular la adherencia y la satisfacción al consumo diario del mismo. En tercer lugar, se analizaron los posibles cambios en las molestias gastrointestinales.

Efficacy and Safety of Single-Dose Zoledronic Acid for Osteoporosis in Frail Elderly Women: A Randomized Clinical Trial. J

JAMA Intern Med. Published online April 13, 2015. doi:10.1001/jamainternmed.2015.0747. In this group of frail elderly women with osteoporosis, 1 dose of zoledronic acid improved BMD over 2 years. The clinical importance of nonsignificant increases in … Leer más

MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

J Clin Invest. 2015 Apr;125(4):1509-22. doi: 10.1172/JCI77716. Epub 2015 Mar 9. Together, our results indicate that miR-188 is a key regulator of the age-related switch between osteogenesis and adipogenesis of BMSCs and may represent a … Leer más

Osteoporosis Treatment and Fracture Outcomes

JAMA Intern Med. Published online April 13, 2015. doi:10.1001/jamainternmed.2015.0757 In this issue of JAMA Internal Medicine, Greenspan and colleagues1 present intriguing data on zoledronic acid, one of the most potent drugs in the bisphosphonate family—if … Leer más

Screening for Osteoporosis

JAMA. 2015 Apr 14;313(14):1467-1468. doi: 10.1001/jama.2015.1064. This JAMA Clinical Guidelines Synopsis article summarizes the most recent National Osteoporosis Foundation guidelines on screening older men and postmenopausal women for osteoporosis. Autor: Altkorn D, Cifu AS.

Arterialized venous bicarbonate is associated with lower bone mineral density and an increased rate of bone loss in older men and women

J Clin Endocrinol Metab. 2015 Apr;100(4):1343-9. doi: 10.1210/jc.2014-4166. Epub 2015 Feb 2. Arterialized plasma HCO3 was associated positively with cross-sectional BMD and inversely with the rate of bone loss, implying that systemic acid-base status is … Leer más

Here comes the sun-is vitamin D a cure for all that ails us?

J Clin Endocrinol Metab. 2015 Apr;100(4):1237-40. doi: 10.1210/jc.2015-1396 Autor: Magge SN.

Switching from tenofovir to abacavir in HIV-1-infected patients with low bone mineral density: changes in bone turnover markers and circulating sclerostin levels

The switch from tenofovir to abacavir seems to induce a positive effect on bone tissue, since bone turnover markers decreased. In addition, circulating sclerostin levels increased, a change associated with improved bone properties.

Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women

The tissue-selective estrogen complex (TSEC) combines bazedoxifene and conjugated estrogens and is designed not only to improve menopausal symptoms and vulvovaginal atrophy but also to prevent bone loss. Therefore, it maintains the benefits of estrogen … Leer más

Antiresorptives and anabolic therapy in sequence or combination for postmenopausal osteoporosis

Sequential antiresorptive therapy is recommended to maintain drug increases in bone mass and support secondary mineralization of the newly formed bone. Combination therapies of antiresorptives and anabolic agents have shown a significant increase in bone … Leer más

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