A particular subset of postmenopausal patients with high remodeling and/or low subchondral bone density may benefit from the treatment with bone-acting agents hindering OA progression. This OA population could be identified with the simultaneous use … Leer más
In our study, postmenopausal women who live in rural populations have more poverty, lower values of vitamin D, lower BMD in the lumbar spine and a higher prevalence of vertebral fractures and of osteoporosis. The … Leer más
Long-term adherence (five years) to diets that feature normal levels of calcium, low protein and low salt may reduce numbers of stone recurrences, decrease oxaluria and calcium oxalate relative supersaturation indexes in people with idiopathic … Leer más
This review describes the most recent data on the effects of glucocorticoids on the Wnt signaling pathway, especially on their antagonists, sclerostin and Dkk-1. Bone formation is suppressed in glucocorticoid-induced osteoporosis. One of the mechanisms … Leer más
HIV infection is associated with an almost 3-fold increase in fracture risk compared to that of uninfected age and gender-matched uninfected patients. HIV patients are also at an almost 9-fold higher risk of hip fracture. … Leer más
After examining results for 10 different bone fracture sites, advanced age appeared the single best possibility for uniting several different sites, resulting in an empirically based composite fracture risk model. Several fracture prediction models that … Leer más
Keeping in mind the premise “living longer, living better”, this commentary is the result of the thoughts, proposals and conclusions obtained after one year working in the framework of this network. Osteoporosis is a worldwide … Leer más
Calcif Tissue Int. 2014 Jun;94(6):597-607. doi: 10.1007/s00223-014-9855-6. Epub 2014 Apr 6. These results provide further evidence that PPI use may increase fracture risk in the elderly and highlight the need for clinicians to periodically reassess … Leer más
Calcif Tissue Int. 2014 Jun;94(6):569-79. doi: 10.1007/s00223-014-9851-x. Epub 2014 Apr 1. The objective of this review is to summarize the recent research on bone cells under microgravity conditions based on advances in the field. Autor: … Leer más
Bone 61 (2014) 138–148. This review examines recent developments in the understanding of why the elderly hip becomes fragile. This growing understanding is suggesting novel testable approaches for reducing risk of hip fracture that might translate … Leer más
