Treatment with biologic drugs is associated with the decrease in bone loss. Studies with anti-TNF blocking agents show preservation or increase in spine and hip BMD and also a better profile of bone markers. Most … Leer más
Osteocalcin (OC) is a vitamin K-dependent protein synthesized during bone formation. Mice injected with the undercarboxylated form of OC (ucOC) had more skeletal muscle mass and less fat mass than sham-treated controls, suggesting a unique … Leer más
Fracture liaison services are recommended as a model of best practice for organizing patient care and secondary fracture prevention for hip fracture patients, although variation exists in how such services are structured. There is considerable … Leer más
Osteocytes play a fundamental role in mechanotransduction and skeletal remodeling. Sex is a determinant of skeletal structure, and female C57BL/6J mice have increased osteoblast number in cancellous bone when compared to male mice. Activation of … Leer más
Total joint replacements for end-stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical improvement.However, robust population based lifetime-risk data for implant revision are not available to aid patient decision making, which … Leer más
Hypophosphatasia (HPP) is the inborn-error-of-metabolism that features low serum alkaline phosphatase (ALP) activity (hypophosphatasemia) caused by loss-of-function mutation(s) of the gene that encodes the tissue-nonspecific isoenzyme of ALP (TNSALP). Autosomal recessive or autosomal dominant inheritance … Leer más
Curso ECTS Formación PhD 2017 Las inscripciones para la 11 ECTS doctorado Curso de Formación ya están abiertas. Haga clic aquí para registrarse y descubre lo que puede esperar de Programa y altavoces. El ECTS … Leer más
El proyecto SEIOMM-UFO coordinado por la Dra. Carmen Gómez Vaquero, reconocido por la IOF como modelo ejemplar en la creación de Unidades de Fractura de excelencia. A unique nationwide initiative is successful in raising … Leer más
