Osteoarthritis (OA) is characterized by degenerative changes in the whole joint leading to physical disability in the elderly population. This condition is associated with altered bone metabolism in subchondral areas suggesting that therapeutic strategies aimed … Leer más
If oversuppression of bone turnover explained the association between bisphosphonate use and atypical subtrochanteric femur fractures (AFF), this could be reversed with anabolic treatment such as teriparatide. They conducted a prospective, open-label study in patients … Leer más
Type 1 and type 2 diabetes are generally accepted to be associated with increased bone fracture risk. However, the pathophysiological mechanisms of diabetic bone disease are poorly understood, and whether the associated increased skeletal fragility … Leer más
This study has as objectives: To estimate the preferences of osteoporotic patients for medication attributes, and analyse data from seven European countries. In total, 1124 patients completed the experiment, with a sample of between 98 … Leer más
HIV infection has been associated with reduced bone mineral density (BMD). Antiretroviral therapy has a deleterious effect on BMD, but its effect on bone fragility is not clear. Long-term treatment with TDF-FTC leads to impaired … Leer más
This meta-analysis aims to determine the effects of regular swimming on bone mineral density (BMD) in young adults (18-30 years). Young adult swimmers present similar BMD values than CG and lower values than HIGH. J … Leer más
Ti-based alloys have increased importance for biomedical applications due to their excellent properties. In particular, the two recently developed TiZrPdSi(Nb) alloys, with a predominant β-Ti phase microstructure, have good mechanical properties, such as a relatively … Leer más
The skeleton is the most common site of colonization by metastatic cancers. Zoledronic acid (ZA) has been shown to be effective for the treatment of bone metastases regardless of whether the bone lesions are osteolytic … Leer más
Bariatric surgery is one of the most common surgeries within developed countries due to the increase in morbid obesity that has been observed in the past decades.The short-term alterations in the metabolism of calcium and … Leer más
Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is associated with an increased prevalence of osteoporosis and osteopenia. They aim to evaluate the use of the World Health Organization Fracture Risk Assessment … Leer más
