Patients with Down syndrome have a number of risk factors that theoretically could predispose them to osteoporosis. In addition, the bone mass of these people may be affected by their anthropometric and body composition peculiarities. In general terms, studies in adults with Down syndrome reported that these people have lower areal bone mineral density (g/cm(2)) than the general population.
Med Clin (Barc). 2017 May 29. pii: S0025-7753(17)30352-. doi:10.1016/j.medcli.2017.04.020
García-Hoyos M, Riancho JA, Valero C