Role and mechanism of action of sclerostin in bone
Bone. 2016 Oct 12. pii: S8756-3282(16)30297-6. doi: 10.1016/j.bone.2016.10.007. [Epub ahead of print] PubMed PMID: 27742498. Autor: Delgado-Calle J, Sato AY, Bellido T.
Parathyroid Hormone Polymorphism RS6254 is Associated with the Development and Severity of Osteoporosis in Asymptomatic but not Normocalcemic Hyperthyroidism
Horm Metab Res. 2016 Oct 18. [Epub ahead of print] PubMed PMID: 27756092. Autor: Díaz-Soto G, Romero E, Pérez-Castrillón JL, Jauregui OI, de Luis Román D.
Efficacy of statins for osteoporosis: a systematic review and meta-analysis
Osteoporos Int. 2016 Nov 25. This meta-analysis assessed the efficacy of statins on the risk of fracture, bone mineral density (BMD), and the markers of bone metabolism by collecting data from 33 clinical trials. They … Leer más
Goal-Directed Treatment for Osteoporosis: A Progress Report from the ASBMR-NOF Working Group on Goal-Directed Treatment for Osteoporosis
J Bone Miner Res. 2016 Nov 19. doi: 10.1002/jbmr.3039. The American Society for Bone and Mineral Research and the United States National Osteoporosis Foundation (NOF) formed a working group to develop principles of goal-directed treatment … Leer más
Association of Muscle Weakness with Post-Fracture Mortality in Older Men and Women: A 25 Year Prospective Study
J Bone Miner Res. 2016 Nov 11. doi: 10.1002/jbmr.3037. Osteoporotic fracture increases the risk of premature mortality. Muscle weakness is associated with both increased fracture risk and low BMD. However, the role of muscle strength … Leer más
Nanocrystallinity effects on osteoblast and osteoclast response to silicon substituted hydroxyapatite (SiHA)
Nanocrystallinity of SiHA affects the cell/biomaterial interface inducing bone cell apoptosis by loss of cell anchorage (anoikis), delaying osteoclast-like cell differentiation and decreasing the resorptive activity of this cell type. These results suggest the potential … Leer más
Oral Microbiota, Periodontal Status and Osteoporosis in Postmenopausal Women
Osteoporosis did not influence the prevalence of periodontitis among postmenopausal women. The presence of periodontopathogenic bacteria was not sufficient to confirm disease. A preventive maintenance program for postmenopausal women, particularly osteoporotic women, who are at … Leer más
Biologic therapies and bone loss in rheumatoid arthritis
Osteoporos Int. 2016 Oct 31. [Epub ahead of print] DOI: 10.1007/s00198-016-3769-2 PMID: 27796445 [PubMed – as supplied by publisher] In this review, the authors present the best evidence available regarding bone loss in RA patients. … Leer más
Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin
J Bone Miner Res 2016, 31: 1791–1802. doi: 10.1002/jbmr.2869 PubMed PMID: 27163932Watch Full Movie Online Streaming Online and Download In the context of glucocorticoid excess, activation of Wnt/β-catenin signaling by Sost/sclerostin deficiency sustains bone integrity … Leer más
Vitamin D Storage in Adipose Tissue of Obese and Normal Weight Women
J Bone Miner Res 2016 DOI: 10.1002/jbmr.2979 PubMed PMID: 27542960 First published: 24 October 2016 In summary, although obese women (OB) had significantly greater total vitamin D stores than non-obese control (C), the relationship between … Leer más
