miR-29b, miR-133b, and miR-211 have direct roles in the vascular smooth muscle calcification induced by high phosphorus and may be new therapeutic targets in the management of vascular calcification.
Even among highly adherent users of oral BP therapy, a minority sustain multiple fractures while on treatment. Older age was predictive of increased risk within both study populations, as was history of recent/old fracture and … Leer más
J Bone Miner Res. 2015 Aug;30(8):1377-85. doi: 10.1002/jbmr.2467. Epub 2015 May 21. In conclusion, FCA decreased dramatically after RYGB, even with most 25OHD levels ≥30 ng/mL and with recommended Ca intake. RYGB patients may need high … Leer más
Several miRNAs may be biomarkers of bone fracture, particularly miR-21-5p.
The results of this pilot study suggest that these fractures are polygenic and are associated with the accumulation of changes in the coding regions of several genes.
Calcif Tissue Int. 2015 Aug;97(2):101-3. doi: 10.1007/s00223-015-0021-6. Epub 2015 Jun 13. Bisphosphonates are extensively used for treatment of children and adults with osteogenesis imperfecta. Over years, studies have reported the response of BP treatment in … Leer más
PLoS One. 2015 Aug 27;10(8):e0132146. doi: 10.1371/journal.pone.0132146. eCollection 2015. CONCLUSION: A fracture liaison nurse in primary care has been associated with a period of improved management. Liaison nurses based in different parts of the health … Leer más
Curr Osteoporos Rep. 2015 Aug;13(4):193-7. doi: 10.1007/s11914-015-0269-9. The study of bones has attracted researchers from many medical fields. To understand bone-organ interactions, hematologists were challenged to investigate bone marrow (BM), the core of bone where … Leer más
The BsmI polymorphism in the VDR gene was not associated with BMD in Spanish postmenopausal women.
In this review we study the pathogenesis of bone changes in alcoholic liver disease and discuss potential therapies.
