In postmenopausal women, bisphosphonates have not been shown to better decrease risk of first fracture compared with calcium and vitamin D therapy alone.
Osteoporos Int 19 may 2015 on line. DOI 10.1007/s00198-015-3168-0 PPI use was associated with fracture in young adults, but overall evidence did not support a PPI-fracture relationship in children. Young adults who use PPIs should … Leer más
Osteoporos Int 19 May online 2015. DOI 10.1007/s00198-015-3160-8 Postmenopausal women aged 50 years and older with a recent DRF had lower bone and muscle strength in both the upper and lower extremities com- pared to … Leer más
COSMOS provides evidence of the association of serum phosphorus, calcium and PTH and mortality, and suggests survival benefits of controlling chronic kidney disease-mineral and bone disorder biochemical parameters in CKD5D patients.
Our data suggest that Glu-OCN-controlled production of Delta like-1 (DLK1) by pancreatic β cells acts as a negative feedback mechanism to counteract the stimulatory effects of insulin on osteoblast production of Glu-OCN, a potential mechanism … Leer más
J Bone Miner Res. 2015 May;30(5):753-64. doi: 10.1002/jbmr.2496. Combined therapy remains a potentially valuable approach to therapy. Because studies of antifracture efficacy comparing combined with single therapy are unlikely to be performed in humans, efforts … Leer más
Journal of Bone and Mineral Research 2015; Volume 30, Issue 6, pages 951–966 The goal of this review is to clarify the biomechanical mechanisms and to make recommendations for systematically evaluating phenotypic changes in mouse … Leer más
Journal of Bone and Mineral Research 2015; Volume 30, Issue 6, pages 970–975 The data show that hyponatremia is associated with up to a doubling in the risk of hip and morphometric spine fractures, independent … Leer más
Prescribed medicines and potentially inappropriate medicines (PIM) and potentially prescribing omissions (PPO) prevalence were high among patients 85 years and over. Benzodiazepine use in those who are prone to falls and omission of calcium and … Leer más
JAMA Intern Med. Published online April 13, 2015. doi:10.1001/jamainternmed.2015.0747. In this group of frail elderly women with osteoporosis, 1 dose of zoledronic acid improved BMD over 2 years. The clinical importance of nonsignificant increases in … Leer más
