Our findings provide additional evidence on the heritability of BMD and a strong genetic correlation between BMD and bone mass/fracture phenotypes in a Spanish population. Our results emphasize the importance of detecting genetic risk factors … Leer más
Although prophylaxis of glucocorticoid-induced osteoporosis in patients with PMR has increased in the recent years, many patients do not receive prophylaxis with bisphosphonate during the first visit.
Prednisone causes damage in systemic lupus erythematosus. Doses <7.5 mg/day and methylprednisolone pulses are not associated with damage accrual
Mandibular cortical width should not be used to predict the risk of bisphosphonate-associated osteonecrosis of the jaws.
Serum sclerostin levels were within the normal range in Hepatitis C virus infected patients, and correlated directly with BMD and serum telopeptide. In addition, the relationships of sclerostin and osteocalcin with variables associated with insulin … Leer más
The management of women with osteoporotic vertebral fractures includes measures to reduce pain providing early mobility, to support the affected spine ensuring fracture healing, as well as starting treatment for osteoporosis itself. Any other underlying … Leer más
Osteoporos Int (2014) 25:2347–2357 To revisit the question posed in the title of this review, is vitamin D a tonic for bone and soft tissue? Probably not, but levels of <25–40 nmol/L do have significant … Leer más
JAMA. 2014 May 28;311(20):2083-91. doi: 10.1001/jama.2014.5052. Vitamin D3 did not reduce the rate of first treatment failure or exacerbation in adults with persistent asthma and vitamin D insufficiency. These findings do not support a strategy … Leer más
JAMA Intern Med. 2014 May 5. doi: 10.1001/jamainternmed.2014.1232. [Epub ahead of print] Among postmenopausal women who discontinue alendronate therapy after 4 to 5 years, age and hip BMD at discontinuation predict clinical fractures during the … Leer más
Bone. 2015 May 24;79:37-42. doi: 10.1016/j.bone.2015.05.022. [Epub ahead of print] The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. Microvesicles (MVs) have received a good deal of attention and … Leer más
