Glucocorticoids and irreversible damage in patients with systemic lupus erythematosus.
Prednisone causes damage in systemic lupus erythematosus. Doses <7.5 mg/day and methylprednisolone pulses are not associated with damage accrual
Mandibular cortical indices on cone-beam computed tomography images in osteoporotic women on treatment with oral bisphosphonates.
Mandibular cortical width should not be used to predict the risk of bisphosphonate-associated osteonecrosis of the jaws.
Serum sclerostin in hepatitis C virus infected patients.
Serum sclerostin levels were within the normal range in Hepatitis C virus infected patients, and correlated directly with BMD and serum telopeptide. In addition, the relationships of sclerostin and osteocalcin with variables associated with insulin … Leer más
EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture.
The management of women with osteoporotic vertebral fractures includes measures to reduce pain providing early mobility, to support the affected spine ensuring fracture healing, as well as starting treatment for osteoporosis itself. Any other underlying … Leer más
Heritability of Bone Mineral Density in a Multivariate Family-Based Study.
Our findings provide additional evidence on the heritability of BMD and a strong genetic correlation between BMD and bone mass/fracture phenotypes in a Spanish population. Our results emphasize the importance of detecting genetic risk factors … Leer más
Longitudinal practice patterns of prophylaxis of glucocorticoid-induced osteoporosis in patients with polymyalgia rheumatica.
Although prophylaxis of glucocorticoid-induced osteoporosis in patients with PMR has increased in the recent years, many patients do not receive prophylaxis with bisphosphonate during the first visit.
SKELETAL AND NONSKELETAL EFFECTS OF VITAMIN D: IS VITAMIN D A TONIC FOR BONE AND OTHER TISSUES?
Osteoporos Int (2014) 25:2347–2357 To revisit the question posed in the title of this review, is vitamin D a tonic for bone and soft tissue? Probably not, but levels of <25–40 nmol/L do have significant … Leer más
Osteoblast-derived microvesicles: A novel mechanism for communication between osteoblasts and osteoclasts
Bone. 2015 May 24;79:37-42. doi: 10.1016/j.bone.2015.05.022. [Epub ahead of print] The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. Microvesicles (MVs) have received a good deal of attention and … Leer más
Fracture Prediction After Discontinuation of 4 to 5 Years of Alendronate Therapy: The FLEX Study
JAMA Intern Med. 2014 May 5. doi: 10.1001/jamainternmed.2014.1232. [Epub ahead of print] Among postmenopausal women who discontinue alendronate therapy after 4 to 5 years, age and hip BMD at discontinuation predict clinical fractures during the … Leer más
Bone Density and Bone Turnover Marker Monitoring After Discontinuation of Alendronate Therapy: An Evidence-Based Decision to Do Less
JAMA Intern Med. 2014 May 5. doi: 10.1001/jamainternmed.2014.162. [Epub ahead of print] The clinical utility of medication monitoring has been a controversial issue in osteoporosis management. In the 1998 and 20012 coverage rules commonly called … Leer más
