Glucocorticoids and irreversible damage in patients with systemic lupus erythematosus.
Prednisone causes damage in systemic lupus erythematosus. Doses <7.5 mg/day and methylprednisolone pulses are not associated with damage accrual
Mandibular cortical indices on cone-beam computed tomography images in osteoporotic women on treatment with oral bisphosphonates.
Mandibular cortical width should not be used to predict the risk of bisphosphonate-associated osteonecrosis of the jaws.
Serum sclerostin in hepatitis C virus infected patients.
Serum sclerostin levels were within the normal range in Hepatitis C virus infected patients, and correlated directly with BMD and serum telopeptide. In addition, the relationships of sclerostin and osteocalcin with variables associated with insulin … Leer más
EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture.
The management of women with osteoporotic vertebral fractures includes measures to reduce pain providing early mobility, to support the affected spine ensuring fracture healing, as well as starting treatment for osteoporosis itself. Any other underlying … Leer más
Heritability of Bone Mineral Density in a Multivariate Family-Based Study.
Our findings provide additional evidence on the heritability of BMD and a strong genetic correlation between BMD and bone mass/fracture phenotypes in a Spanish population. Our results emphasize the importance of detecting genetic risk factors … Leer más
Longitudinal practice patterns of prophylaxis of glucocorticoid-induced osteoporosis in patients with polymyalgia rheumatica.
Although prophylaxis of glucocorticoid-induced osteoporosis in patients with PMR has increased in the recent years, many patients do not receive prophylaxis with bisphosphonate during the first visit.
SKELETAL AND NONSKELETAL EFFECTS OF VITAMIN D: IS VITAMIN D A TONIC FOR BONE AND OTHER TISSUES?
Osteoporos Int (2014) 25:2347–2357 To revisit the question posed in the title of this review, is vitamin D a tonic for bone and soft tissue? Probably not, but levels of <25–40 nmol/L do have significant … Leer más
Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture
Bone 2014; 62:22-28 Notch1 and Notch2 inactivation increased porosity and reduced thickness of cortical bone. These effects were modest and more evident in 3 and 6 month old female than in male mice of the same … Leer más
Waning predictive value of serum adiponectin for fracture risk in elderly men
MrOs Sweden. Osteoporos Int 2014;25:1831-1836 Serum adiponectin is a risk factor for fracture. Nevertheless, the predictive value attenuates with time so that its use for the risk assessment in the long term is questionable. This … Leer más
Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial
JAMA. 2014 May 28;311(20):2083-91. doi: 10.1001/jama.2014.5052. Vitamin D3 did not reduce the rate of first treatment failure or exacerbation in adults with persistent asthma and vitamin D insufficiency. These findings do not support a strategy … Leer más
