The results suggest that deletions in the 6p25.1 locus may predispose to higher risk of fracture in a subset of populations of European origin; larger and geographically restricted studies will be needed to confirm this … Leer más
Self-reported hip fracture is a common condition among community-living elderly population in Spain, and has a significant impact upon long-term all-cause mortality. There is a paucity of data concerning the specific associations between hip fracture … Leer más
In our study, postmenopausal women who live in rural populations have more poverty, lower values of vitamin D, lower BMD in the lumbar spine and a higher prevalence of vertebral fractures and of osteoporosis. The … Leer más
Patients with chronic hepatitis C have low bone mass associated with increased bone resorption, and some relationship can be expected between serum aminotransferase levels and the degree of bone mass loss. Bone mass may be … Leer más
No differences in BMD were found between patients and controls. As for 25OHD, a lack of its expected summer rise was observed. It is doubtful whether this has any homeostatic consequence. We consider that the … Leer más
Multiple juxta-articular deposits of hydroxyapatite causing calcific periarthritis may be a useful sign of hypophosphatasia, especially when the calcific periarthritis is familial. ypophosphatasia (HPP) is the inborn error of metabolism that features low serum alkaline … Leer más
The impact on the population of the different recommendations is enormous, varying from 17% to 80% of the population over 50 who would be tested Although in men it seems that a clinical rationale exists … Leer más
Long-term adherence (five years) to diets that feature normal levels of calcium, low protein and low salt may reduce numbers of stone recurrences, decrease oxaluria and calcium oxalate relative supersaturation indexes in people with idiopathic … Leer más
PTH (1-84) is able to restore the adverse effects of orchidectomy on bone as measured by BMD, microstructural and biomechanical properties and bone remodeling markers. The purpose of this study was to evaluate the effect … Leer más
Circulating sclerostin levels are significantly increased in patients with prostate cancer and particularly in those receiving androgen deprivation therapy. The inverse relationship between serum sclerostin and testosterone in these patients suggests that androgens are key … Leer más
