The trabecular bone score (TBS) is a gray‐level textural metric that can be extracted from the two‐dimensional lumbar spine dual‐energy X‐ray absorptiometry (DXA) image. TBS is related to bone microarchitecture and provides skeletal information that … Leer más
J Clin Invest. 2014 Apr 1;124(4):1-13. doi: 10.1172/JCI72323. Epub 2014 Mar 18. Together, these results underscore the involvement of bone, among other tissues, in the disruption of whole-body glucose homeostasis resulting from a HFD and … Leer más
Osteoporos Int (2014) 25:1267–1274. DOI 10.1007/s00198-013-2586-0. Conclusions This study supports other international studies by showing changes in the incidence of hip fractures after age population adjustment, which denotes a decrease in the younger age groups … Leer más
In conclusion, our data highlight the potential for novel drug targeting approaches in rare skeletal disorders ranging from severe skeletal fragility to sclerosing bone overgrowth through selective modulation of canonical WNT signaling. These approaches should … Leer más
Calcified Tissue International (2014) 94:4: 423-432 They conclude that Cnr2 deficiency affects expression of a large number of genes in different strains of mice, and that these differences are likely to be responsible in part … Leer más
The results of this nested case–control study in the CPRD indicate no evidence for a higher risk of MI or cardiovascular death associated with the use of strontium ranelate in women treated for osteoporosis compared … Leer más
Osteoporos Int (2014) 25:1225–1235 This is the first network meta-analysis to assess the comparative GI safety of bisphosphonates for primary osteoporosis. Our results identify zoledronic acid as having the highest probability of having the greatest … Leer más
J Bone Miner Res, (2014) 29; 787–795 The findings represent the first demonstration, using a direct in vivo measure of BMS, of compromised bone material properties in patients with T2D. Further, our results confirm previous … Leer más
In conclusion, baseline cardiovascular diseases are common in patients treated with strontium ranelate, with more than half of strontium ranelate users being current users of antiplatelet drugs or having a history of cerebrovascular disease, peripheral … Leer más
Froedtert Healthcare, Patient Care Services, Milwaukee, WI, USA, ryanpa@uwm.edu. Ryan P, Schlidt A, Ryan C Froedtert Healthcare, Patient Care Services, Milwaukee, WI, USA, ryanpa@uwm.edu. Osteoporosis International : a Journal Established as Result of Cooperation Between … Leer más
