Endocrinol Metab Clin North Am. 2015;44:517-30. Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue leading to decreased bone strength and an increased risk of low-energy fractures. Central dual-energy X-ray absorptiometry … Leer más
Calcif Tissue Int. 2015 Sep;97(3):199-200. doi: 10.1007/s00223-015-0012-7. Epub 2015 May 13. Autor: Burr DB, Allen MR.
Osteoporos Int. 2015 Sep;26(9):2223-41. doi: 10.1007/s00198-015-3149-3. Epub 2015 May 5. In this review, we summarize our current understanding of the pathophysiology of fragility fractures that occur for the first time during pregnancy and lactation, and … Leer más
Osteoporos Int. 2015 Sep;26(9):2257-63. doi: 10.1007/s00198-015-3117-y. Epub 2015 Apr 10. The available data also showed that patients attending the FLSs were evaluated, treated and followed in high compliancy with the IOF standards. Some standards are … Leer más
Osteoporos Int. 2015 Sep;26(9):2355-63. doi: 10.1007/s00198-015-3148-4. Epub 2015 May 6. Compared with placebo, bisphosphonates could decrease the risk of vertebral and non-vertebral fractures, reduce BSAP and CTX, and increase BMD in men with osteoporosis. Autor: … Leer más
The pharmacological management of osteoporosis in women of 50 and over in this population combines an important overuse and, to a lesser extent, underuse, although the level of inappropriateness varied strikingly depending on the CPG … Leer más
We identified quantitative trait loci (QTLs) for structure phenotypes on chromosomes 3, 8, 10, 12, 17 and 20, and QTLs for strength phenotypes on chromosomes 5, 10 and 11 that met a conservative genome-wide empiric … Leer más
In this review, we discuss the current concepts about the cellular and molecular mechanisms whereby PTHrP may induce anabolic actions in bone. Pre-clinical studies and clinical data using N-terminal PTHrP analogs are also summarized, pointing … Leer más
Most of the 13 tools are feasible in clinical practice. FRAX has the largest number of externally validated and independent studies. The overall accuracy of the different tools is satisfactory (>0.70), with QFracture reaching 0.89 … Leer más
These findings suggest for the first time that dabigatran has a better bone safety profile than warfarin, as warfarin treatment affects bone by reducing trabecular size and structure, increasing turnover and reducing mineralization. These differences … Leer más
