FASEB J. 2015 Jan 28. pii: fj.14-259085. [Epub ahead of print] In summary, our findings demonstrate that EPO negatively regulates bone mass and thus bears significant clinical implications for the potential management of patients with … Leer más
J Bone Miner Res. 2015 Jan;30(1):3-23. doi: 10.1002/jbmr.2405. Prevention strategies for ONJ include elimination or stabilization of oral disease prior to initiation of antiresorptive agents, as well as maintenance of good oral hygiene. In those … Leer más
J Clin Endocrinol Metab. 2015 Jan;100(1):90-9. doi: 10.1210/jc.2014-2646. Reference intervals for BTMs in older men have been defined. tOC may be more informative for hip fracture risk in older men than CTX-I and PINP. Further … Leer más
Bone. 2015 Jan;70C:2-9. doi: 10.1016/j.bone.2014.08.011. Current interest in stem cells in bone as in other fields is intertwined with that shift. New opportunities and also new challenges arise. This article is part of a Special … Leer más
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201409857. Thus, activation of osteocytic β-catenin signaling increases both osteoclasts and osteoblasts, leading to bone gain, and is sufficient to activate the Notch pathway. … Leer más
Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs). Autor: Worthley DL, Churchill M, Compton JT, Tailor Y, Rao … Leer más
In conclusion, administration of oral and intravenous bisphosphonates was associated with increased bone mineral density at the lumbar spine and total hip over two years in HIV-positive patients. However, none of the included trials were … Leer más
Although interesting data on relief of vasomotor symptoms have been reported for DT56a, further clinical studies with a greater number of cases and a longer period of study are required to correctly identify its indications … Leer más
For most conditions, the available evidence is limited. Special attention should be paid to possible contraindications of drugs used for the treatment of postmenopausal or senile osteoporosis. Bisphosphonates are the most widely used drugs in … Leer más
Journal of Bone and Mineral Research, Volume 29, Issue 12, pages 2594–2600. doi: 10.1002/jbmr.2291. In conclusion, the estimated femoral strength from FE analysis of DXA scans is an independent predictor and performs at least as … Leer más
