Aging may enhance both oxidative stress and bone-marrow mesenchymal stem-cell (MSC) differentiation into adipocytes. That reduces osteoblastogenesis, thus favoring bone-mass loss and fracture, representing an important worldwide health-issue, mainly in countries with aging populations. Intake of antioxidant products may help to retain bone-mass density.
Exp Gerontol. 2017 Feb 3;90:71-78. doi: 10.1016/j.exger.2017.01.024.
Casado-Díaz A, Túnez-Fiñana I, Mata-Granados JM, Ruiz-Méndez MV,Dorado G, Romero-Sánchez MC, Navarro-Valverde C, Quesada-Gómez JM.