J Bone Miner Res. 2016 Apr;31(4):815-27. doi: 10.1002/jbmr.2741. Epub 2015 Dec 14. Our data identify osteocyte autophagy as a new potential target in MM bone disease and support the use of PIs to maintain osteocyte … Leer más
J Bone Miner Res. 2016 Apr;31(4):874-81. doi: 10.1002/jbmr.2782. Epub 2016 Jan 24 We demonstrate that impaired sclerostin binding to the mutated LRP4 protein leads to dramatic increase in circulating sclerostin in this patient. With this … Leer más
J Clin Endocrinol Metab. 2016 Apr;101(4):1353-63. doi: 10.1210/jc.2015-4181. Epub 2016 Feb 9 We compared effects of teriparatide and denosumab on PTH, bone turnover markers, and bone histomorphometry in osteoporotic postmenopausal women. The findings were inconsistent … Leer más
J Clin Endocrinol Metab. 2016 Apr;101(4):1498-505. doi: 10.1210/jc.2015-3698. Epub 2016 Feb 22 TPTD stimulates bone formation rapidly in cancellous and endocortical envelopes of the FN. Our findings provide a mechanistic basis for TPTD-mediated improvement in … Leer más
Osteoporos Int. 2016 Apr;27(4):1281-386. doi: 10.1007/s00198-015-3440-3. Epub 2016 Feb 8. Erratum in: Osteoporos Int. 2016 Apr;27(4):1387. The best evidence (grade A) is available for positive effects of calcium intake and physical activity, especially during the … Leer más
Osteoporos Int. 2016 Apr;27(4):1281-386. doi: 10.1007/s00198-015-3440-3. Epub 2016 Feb 8 The best evidence (grade A) is available for positive effects of calcium intake and physical activity, especially during the late childhood and peripubertal years-a critical … Leer más
Osteoporos Int. 2016 Apr;27(4):1425-40. doi: 10.1007/s00198-015-3367-8. Epub 2015 Oct 16. Review Supplementation with calcium and vitamin D is often necessary in the SOT population due to a high incidence of vitamin D deficiency. Bisphosphonate therapy … Leer más
Conjugated estrogens/bazedoxifene improved vasomotor symptoms, genitourinary syndrome of menopause, and BMD in Latin American women, with efficacy/safety similar to the global population.
J Clin Endocrinol Metab. 2016 Apr;101(4):1353-63. doi: 10.1210/jc.2015-4181. Epub 2016 Feb 9. We compared effects of teriparatide and denosumab on PTH, bone turnover markers, and bone histomorphometry in osteoporotic postmenopausal women. The findings were inconsistent … Leer más
J Clin Endocrinol Metab. 2016 Apr;101(4):1414-21. doi: 10.1210/jc.2015-4017. Epub 2016 Feb 10. In this large, prospective, observational cohort study of postmenopausal women in the WHI, Cox proportional hazard regression models showed that sodium intake at … Leer más
