Role of Periostin in Adhesion and Migration of Bone Remodeling Cells
Role of Periostin in Adhesion and Migration of Bone Remodeling Cells
Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study
The introduction and/or expansion of orthogeriatric and FLS models of post-hip fracture care has a beneficial effect on subsequent mortality. No evidence for a reduction in second hip fracture rate was found.
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data
An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Within a strategy of a disease modifying approach to inflammatory disease, short durations of moderate doses of … Leer más
The COL1A1 SP1 polymorphism is associated with lower bone mineral density in patients treated with valproic acid
In our study, the presence of the ‘s’ allele of the COL1A1 Sp1 polymorphism in individuals with epilepsy was related to lower bone BMD (lumbar and femoral). This relationship seemed to be further apparent in … Leer más
FGF23-regulated production of Fetuin-A (AHSG) in osteocytes
Bone. 2016 Feb;83:35-47. doi: 10.1016/j.bone.2015.10.008. Epub 2015 Oct 23. Our data not only confirm that AHSG is produced in bone, mainly in osteocytes, but show for the first time that its production is modulated by … Leer más
Fracture experience among participants from the FROCAT study: what thresholding is appropriate using the FRAX tool?
Our findings support and validate the use of FRIDEX thresholds of FRAX when discussing the risk of fracture and the initiation of therapy with patients.
The Microbiome and Musculoskeletal Conditions of Aging: A Review of Evidence for Impact and Potential Therapeutics
J Bone Miner Res. 2016 Feb;31(2):261-9. doi: 10.1002/jbmr.2765. Review. This perspective discusses evidence to date on the role of the microbiome and the highly prevalent age-related disorders of osteoporosis, osteoarthritis, gout, rheumatoid arthritis, sarcopenia, and … Leer más
Relationship between spinal osteoarthritis and vertebral fractures in men older than 50 years: data from the Camargo Cohort Study
Our results suggest a positive relationship between radiologic osteoarthritic changes at the thoracic spine and prevalent vertebral fractures in men more than 50 years of age. Osteoarthritis may act as a local risk factor, in … Leer más
Contribution of Lumbar Spine BMD to Fracture Risk in Individuals With T-Score Discordance
J Bone Miner Res. 2016 Feb;31(2):274-80. doi: 10.1002/jbmr.2611. Epub 2015 Sep 3. This study shows the significant contribution of lower LS BMD to fracture risk over and above FN BMD in women. A LS BMD … Leer más
Medication-related osteonecrosis of the jaw associated with bisphosphonates and denosumab in osteoporosis
Most of our cases were in the early stages of MRONJ, and the success rate after conservative treatment was high.
