Our results suggest that the CD40/CD40L system plays a role in regulating BMD. Effectively, our data suggest that a decreased production of OPG could be the cause of the lower BMD observed in TT women … Leer más
J Bone Miner Res. 2015 Dec;30 (12):2140-2149. doi: 10.1002/jbmr.2735. Epub 2018 Nov 4. Review. Collectively, this developing area of osteoimmunology raises new questions and promises to provide novel insights into pathophysiologic conditions as well as … Leer más
Osteoporos Int. 2015 Dec;26(12):2743-57. doi: 10.1007/s00198-015-3272-1. Epub 2015 Aug 6. This review presents the current knowledge on hypophosphatasia, a rare genetic disease of very variable severity (from lethal to mild) and clinical presentation, caused by … Leer más
Both cortical and trabecular vBMD are reduced at the proximal femur in ACRO patients, regardless of gender, gonadal status and disease activity. Disease duration is negatively associated with trabecular vBMD at the total hip and … Leer más
J Clin Endocrinol Metab. 2015 Dec;100(12):4662-8. doi: 10.1210/jc.2015-2957. Epub 2015 Oct 27. Bone turnover markers were significantly but modestly associated with bone turnover parameters measured in iliac cancellous bone. The iliac crest bone may not … Leer más
No significant effect in TBS was observed in liver transplant patients treated with RIS or calcium and vitamin D3 after 1 year of follow-up. In these patients the clinical usefulness of this new tool should … Leer más
Osteoporos Int. 2015 Dec 22. [Epub ahead of print] Studies are urgently needed to i) prove the underlying pathophysiological processes suggested above, ii) establish the predictive criteria exposing patients to an increased risk of RVF, … Leer más
Taking together these results indicate for the first time that mesenchymal stem cells have significant differences in their proliferative, pluripotency and metabolism profiles and those differences are age depending.
Overall, in addition to the weight loss promoting properties of calcium, on its own or co-supplemented with conjugated linoleic acid, our results support beneficial effects on bone metabolism in mice.
J Clin Endocrinol Metab. 2015 Nov;100(11):4208-14. doi: 10.1210/jc.2015-2829. Epub 2015 Sep 10 CONCLUSIONS: These findings lead us to conclude that premenopausal women with IOP, particularly those over 40, may require antiresorptive treatment to prevent bone … Leer más
