Bone changes in alcoholic liver disease
In this review we study the pathogenesis of bone changes in alcoholic liver disease and discuss potential therapies.
Risk factors for the development of osteoporosis after spinal cord injury. A 12-month follow-up study
The evaluation of BMD at the lumbar spine and femur short-term after spinal cord injury (SCI) is a simple, effective method for predicting the development of osteoporosis during the first year after SCI. Our results … Leer más
Serum 25-Hydroxyvitamin D Levels: Variability, Knowledge Gaps, and the Concept of a Desirable Range
J Bone Miner Res. 2015 Jul;30(7):1119-33. doi: 10.1002/jbmr.2536. Epub 2015 May 7. We propose a desirable range of 20 to 40 ng/mL (50 to 100 nmol/L), provided precise and accurate assays are used. Although slightly lower levels, … Leer más
Effects of Denosumab and Calcitriol on Severe Secondary Hyperparathyroidism in Dialysis Patients With Low Bone Mass
. J Clin Endocrinol Metab. 2015 Jul;100(7):2784-2792. Epub 2015 May 8 Denosumab allows for supra-physiologic doses of calcitriol resulting in decreased parathyroid secretion and parathyroid hyperplasia. Supervised administration and weekly laboratory and clinical monitoring of … Leer más
Incidence of hip fracture in Spain (1997-2010)
The analysis of the incidence of hip fracture in Spain in people≥65 year old shows a significant variability between AA. CC. Except in Canary Islands, this variability is difficult to explain only by factors such … Leer más
The influence of genetic variability and proinflammatory status on the development of bone disease in patients with Gaucher disease
The data suggest that patients with type 1 Gaucher disease (GD1) have increased susceptibility to developing bone disease owing to the coexistence of genetic variants, and that genetic background in GD1 is fundamental to regulate … Leer más
Comparison of two different strategies of treatment with zoledronate in HIV-infected patients with low bone mineral density: single dose versus two doses in 2 years
The benefits for BMD of a single dose of zoledronate in 2 years may be comparable to those obtained with two doses of the drug after 96 weeks, although this study is insufficiently powered to … Leer más
Establishing Biomechanical Mechanisms in Mouse Models: Practical Guidelines for Systematically Evaluating Phenotypic Changes in the Diaphyses of Long Bones
Journal of Bone and Mineral Research 2015; Volume 30, Issue 6, pages 951–966 The goal of this review is to clarify the biomechanical mechanisms and to make recommendations for systematically evaluating phenotypic changes in mouse … Leer más
Hyponatremia and Fractures: Findings From the MrOS Study
Journal of Bone and Mineral Research 2015; Volume 30, Issue 6, pages 970–975 The data show that hyponatremia is associated with up to a doubling in the risk of hip and morphometric spine fractures, independent … Leer más
