Here comes the sun-is vitamin D a cure for all that ails us?
J Clin Endocrinol Metab. 2015 Apr;100(4):1237-40. doi: 10.1210/jc.2015-1396 Autor: Magge SN.
Switching from tenofovir to abacavir in HIV-1-infected patients with low bone mineral density: changes in bone turnover markers and circulating sclerostin levels
The switch from tenofovir to abacavir seems to induce a positive effect on bone tissue, since bone turnover markers decreased. In addition, circulating sclerostin levels increased, a change associated with improved bone properties.
Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women
The tissue-selective estrogen complex (TSEC) combines bazedoxifene and conjugated estrogens and is designed not only to improve menopausal symptoms and vulvovaginal atrophy but also to prevent bone loss. Therefore, it maintains the benefits of estrogen … Leer más
The importance of calciuria as lithogenic factors in patients with osteopenia/osteoporosis.
Patients with osteopenia/osteoporosis without lithiasis present some urinary biochemical alterations. This would explain the lack of lithogenic activity, although low calcium excretion in 24-h urine samples is a protective factor against the loss of bone … Leer más
The effects of swimming training on bone tissue in adolescence.
Although more information is needed for females, it seems that for males, swimming is associated with lower BMC and BMD.
Adjusting Fracture Probability by Trabecular Bone Score
Calcif Tissue Int (2015) 96:500–509 DOI 10.1007/s00223-015-9980-x They have demonstrated that lumbar spine texture analysis using TBS is a risk factor for osteoporotic fracture and also for risk of death. The predictive ability of TBS … Leer más
WNT5A Has Anti-Prostate Cancer Effects In Vitro and Reduces Tumor Growth in the Skeleton In Vivo
J Bone Miner Res. 2015 Mar;30(3):488-97- Using different osteotropic human prostate cancer cell lines, the influence of WNT5A overexpression and knock-down on proliferation, migration, and apoptosis was assessed. In vitro, WNT5A overexpression induced prostate cancer … Leer más
Connexin 43 channels are essential for normal bone structure and osteocyte viability
J Bone Miner Res. 2015 Mar;30(3):436-48. doi: 10.1002/jbmr.2374. These findings suggest that osteocytic Cx43 channels play distinctive roles in the bone; hemichannels play a dominant role in regulating osteocyte survival, endocortical bone resorption, and periosteal … Leer más
The choice of normative pediatric reference database changes spine bone mineral density z-scores but not the relationship between bone mineral density and prevalent vertebral fractures
J Clin Endocrinol Metab. 2015 Mar;100(3):1018-27. doi: 10.1210/jc.2014-3096. Epub 2014 Dec 11. Although the use of a LSBMD Z-score threshold as part of the definition of osteoporosis in a child with VF does not appear … Leer más
Serum uric acid is associated with quantitative ultrasound parameters in men: data from the Camargo cohor
Higher serum uric acid levels in men older than 50 years are positively associated with QUS parameters. These data might suggest a better bone quality in men with elevated serum uric acid values.
