At 7 years, the cumulative incidences of new vertebral fractures were significantly lower in the bazedoxifene (6.4%) and bazedoxifene 20 mg (7.6%) groups than in the placebo group (9.9%); the relative risk reductions were 36.5% … Leer más
Regardless of differences in health care delivery systems and medication reimbursement plans, the use of osteoporosis medications for the secondary prevention of osteoporotic fracture was low. Adherence to osteoporosis treatment was also suboptimal with the … Leer más
Calcif Tissue Int (2015) 96:500–509 DOI 10.1007/s00223-015-9980-x They have demonstrated that lumbar spine texture analysis using TBS is a risk factor for osteoporotic fracture and also for risk of death. The predictive ability of TBS … Leer más
J Bone Miner Res. 2015 Mar;30(3):488-97- Using different osteotropic human prostate cancer cell lines, the influence of WNT5A overexpression and knock-down on proliferation, migration, and apoptosis was assessed. In vitro, WNT5A overexpression induced prostate cancer … Leer más
J Clin Endocrinol Metab. 2015 Mar;100(3):1018-27. doi: 10.1210/jc.2014-3096. Epub 2014 Dec 11. Although the use of a LSBMD Z-score threshold as part of the definition of osteoporosis in a child with VF does not appear … Leer más
Am J Kidney Dis. 2015 Feb;65(2):240-8. doi:10.1053/j.ajkd.2014.07.007. Lower serum bicarbonate levels are associated with lower BMD in US adults. Further studies should examine whether serum bicarbonate levels should be incorporated into the diagnostic assessment and … Leer más
J Bone Miner Res. 2015 Feb;30(2):216-24. doi: 10.1002/jbmr.2351. These results support further study of blosozumab as a potential anabolic therapy for osteoporosis. Autor: ReckerRR,BensonCT,MatsumotoT,BologneseMA,RobinsDA,A J,ChiangAY,Hu L,Krege JH, Sowa H,Mitlak BH,M SL
J Clin Endocrinol Metab. 2015 Feb;100(2):679-83. doi: 10.1210/jc.2014-3777. The low correlation between past and future BMD loss helps explain why the rate of BMD loss is unlikely to be helpful for refining fracture risk. Autor: … Leer más
Clin Endocrinol Metab. 2015 Feb;100(2):475-82. doi: 10.1210/jc.2014-2047. The inverse association between lumbar spine TBS and insulin resistance may make it an indicator for determining skeletal deterioration in diabetic patients who have high BMD. Autor: Kim … Leer más
Osteoporos Int. 2015 Feb;26(2):449-58. doi: 10.1007/s00198-014-2813-3 The meta-analysis indicates that BMD is low in predialysis and dialysis patients with fractures. These findings, considered together with the recent prospective study in CKD, and post hoc analyses … Leer más
