Hormonal therapy (HT) is considered the treatment of choice to alleviate the symptoms of hypoestrogenism and to prevent long-term consequences. We suggest that HT should be continued until at least age 51, the average age … Leer más
Women with low adherence to oral bisphosphonates reported greater treatment satisfaction when transitioned to denosumab versus switching to a monthly oral bisphosphonate
A therapeutic approach to osteosarcopenic obesity aimed at the prevention of falls must include several factors, and act on those risk elements which can be effectively modified.
Altogether, these results further suggest that, in addition to osteocalcin, other bone-derived signals affect white adipose tissue and energy expenditure contributing to the regulation of energy metabolism.
Wealthiest areas have an almost 30% increased risk of hip fracture compared to the most deprived. Differences in age-sex composition and a higher prevalence of obesity in deprived areas could explain this higher risk.
Short-term after spinal cord injury there is a marked increase in bone turnover and bone loss, the latter associated with an increase in Dkk-1 serum levels. The persistence of increased levels of this Wnt antagonist … Leer más
J Bone Miner Res. 2015 Jan;30(1):3-23. doi: 10.1002/jbmr.2405. Prevention strategies for ONJ include elimination or stabilization of oral disease prior to initiation of antiresorptive agents, as well as maintenance of good oral hygiene. In those … Leer más
Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. Grem1 expression identifies distinct connective tissue stem cells in both the bone (OCR stem cells) and the intestine (iRSCs). Autor: Worthley DL, Churchill M, Compton JT, Tailor Y, Rao … Leer más
J Bone Miner Res. 2015 Jan;30(1):39-45. doi: 10.1002/jbmr.2315. Together, these findings suggest that the use of denosumab and teriparatide in combination improves HR-pQCT measures of bone quality more than either drug alone and may be … Leer más
J Clin Endocrinol Metab. 2015 Jan;100(1):90-9. doi: 10.1210/jc.2014-2646. Reference intervals for BTMs in older men have been defined. tOC may be more informative for hip fracture risk in older men than CTX-I and PINP. Further … Leer más
