Hip fractures continue to increase in absolute numbers, although if the rates are adjusted for age, a downward trend is seen in certain age groups. These findings have various origins, although in the absence of … Leer más
The findings suggest a trend to stabilize the incidence of hip fracture in the Canary Islands due to a decrease in men, while in women, the incidence increased.
As expected, TBS of Naive subjects decreased with age. As expected a TBS preservation has been observed under Alendronate and Risedronate. Testosterone and Calcium and Vitamin D effects on TBS were evaluated for the first … Leer más
Altogether, these results further suggest that, in addition to osteocalcin, other bone-derived signals affect white adipose tissue and energy expenditure contributing to the regulation of energy metabolism.
Wealthiest areas have an almost 30% increased risk of hip fracture compared to the most deprived. Differences in age-sex composition and a higher prevalence of obesity in deprived areas could explain this higher risk.
Short-term after spinal cord injury there is a marked increase in bone turnover and bone loss, the latter associated with an increase in Dkk-1 serum levels. The persistence of increased levels of this Wnt antagonist … Leer más
Women with low adherence to oral bisphosphonates reported greater treatment satisfaction when transitioned to denosumab versus switching to a monthly oral bisphosphonate
A therapeutic approach to osteosarcopenic obesity aimed at the prevention of falls must include several factors, and act on those risk elements which can be effectively modified.
J Bone Miner Res. 2015 Jan;30(1):165-75. doi: 10.1002/jbmr.2311. In conclusion, current evidence does not support the hypothesis that calcium supplementation with or without vitamin D increases coronary heart disease or all-cause mortality risk in elderly … Leer más
Proc Natl Acad Sci U S A. 2015 Jan 20. pii: 201409857. Thus, activation of osteocytic β-catenin signaling increases both osteoclasts and osteoblasts, leading to bone gain, and is sufficient to activate the Notch pathway. … Leer más
