J Bone Miner Res. 2014 Nov;29(11):2357-68. doi: 10.1002/jbmr.2267. As in humans, FD lesions in mice developed only in the postnatal life; a defined spatial and temporal pattern characterized the onset and progression of lesions across … Leer más
Bone 67; 246–256. doi: 10.1016/j.bone.2014.07.014. Epub 2014 Jul 15 Studies using dual-energy X-ray absorptiometry and quantitative computed tomography for longitudinal assessment of changes at the hip have consistently shown increases in areal and volumetric bone … Leer más
These in vitro findings point to caveolin-1-dependent VEGFR2 activation as an important mechanism whereby mechanical stimuli promote osteocyte viability
Patients with recurrent calcium nephrolithiasis and fasting hypercalciuria have a higher incidence of osteopenia and osteoporosis. They present increased BTMs (mainly resorptive) and up to 30% have hypocitraturia and increased urinary calcium/citrate ratio (>0.25). Medical … Leer más
Endogenous estrogens partially reduce atherogenic burden in female apolipoprotein E-deficient mice. Ovariectomy increases bone resorption, but not under exacerbated proatherogenic conditions induced by high-fat diet. The absence of apolipoprotein E might have an influence on … Leer más
Osteoporosis and fragility fracture have been diagnosed, although rarely. The condition, however, is transitory because there is no long-term data supporting the deleterious effect of pregnancy on bone mass or fracture risk. Prevention is limited … Leer más
We conclude that patients receiving cinacalcet on dialysis presented similar serum phosphate levels but higher PTH and serum calcium levels during the initial six months after kidney transplantation than cinacalcet non-treated patients. The group previously … Leer más
The European Society of AIDS (EACS), and other societies, have included guidance on management of osteoporosis in HIV-infected patients emphasizing the identification of patients with low bone mass. Supplementation of calcium and vitamin D and … Leer más
The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) recommends optimal dietary protein intake of 1.0-1.2g/kgbodyweight/d with at least 20-25g of high-quality protein at each main meal, with adequate vitamin D … Leer más
We have demonstrated in vivo a key role of nuclear factor erythroid derived 2-related factor-2 (Nrf2) in the maintenance of bone microarchitecture.
