Spanish Menopause Society position statement: Use of denosumab in postmenopausal women.
A panel of experts from the Spanish Menopause Society has met to develop usage recommendations based on the best available evidence.
The Association between Nutritional Screening Via The Conut Index And Bone Mineral Density In Chronic Liver Disease of Various Etiologies.
Malnutrition assessed by CONUT was very frequent in patients with liver cirrhosis. CONUT score inversely correlated with liver function, while malnutrition stage directly correlated with BMD, fracture risk, and 25(OH)-D3. Total cholesterol showed a negative … Leer más
Effect of lysophosphatidic acid receptor inhibition on bone changes in ovariectomized mice.
Pharmacological inhibition of lysophosphatidic acid receptorwas not beneficial for preventing bone loss in ovariectomized mice, indicating that its favorable effect on bone remodeling is less general than hypothesized.
An ex vivo model in human femoral heads for histopathological study and resonance frequency analysis of dental implant primary stability.
Although resonance frequency analysis (RFA)-assessed implant stability (ISQ values) are not correlated with morphometric parameters, they can discriminate bone quality (osteoporosis versus osteoarthritis). This ex vivo model is useful for dental implant studies.
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop
J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9. doi: 10.1210/jc.2014-1413. Epub 2014 Aug 27. In view of new findings since the last International Workshop on the Management of Asymptomatic PHPT, guidelines for management have been revised. The … Leer más
CLINICAL PRESENTATION OF PAGET’S DISEASE: EVALUATION OF A CONTEMPORARY COHORT AND SYSTEMATIC REVIEW
Calcif Tissue Int. 2014 Nov;95(5):385-92. doi: 10.1007/s00223-014-9904-1. Epub 2014 Aug 27. While changes in the mode of presentation of PDB have occurred over recent years, many patients present with complications such as fracture and deformity. … Leer más
Medical management of primary hyperparathyroidism: proceedings of the fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism
J Clin Endocrinol Metab. 2014 Oct;99(10):3607-18. doi: 10.1210/jc.2014-1417. Epub 2014 Aug 27 The recommended calcium intake in patients with PHPT should follow guidelines established for all individuals. It is not recommended to limit calcium intake … Leer más
Effects of eight-month treatment with ONO-5334, a cathepsin K inhibitor, on bone metabolism, strength and microstructure in ovariectomized cynomolgus monkeys
Bone. 2014 Apr 27;65C:1-8. doi: 10.1016/j.bone.2014.04.023. In microstructural analysis, alendronate suppressed OVX-induced increase in femoral mid-shaft osteonal bone formation rate (BFR) to a level below that recorded in the sham group, whereas ONO-5334 (Catepsin K … Leer más
Inflammatory factors in the circulation of patients with active rheumatoid arthritis stimulate osteoclastogenesis via endogenous cytokine production by osteoblasts
Osteoporos Int 2014; Oct;25(10):2453-63. doi: 10.1007/s00198-014-2779-1. Epub 2014 Jul 16 The combination of cytokines present in serum of RA patients with active disease might contribute to bone loss by directly inhibiting osteoblast proliferation and differentiation, … Leer más
Secular trends in hip fractures worldwide: opposing trends East versus west
J Bone Miner Res. 2014 Aug;29(8):1745-55. doi: 10.1002/jbmr.2218. Data presented here show close parallels between rising rates of urbanization and hip fractures across disparate geographic locations and cultures. Once the proportion of the urban population … Leer más
