BINDING KINETICS OF A FLUORESCENTLY LABELED BISPHOSPHONATE AS A TOOL FOR DYNAMIC MONITORING OF BONE MINERAL DEPOSITION IN VIVO

JBMR 2014; 29(9) 1993-2003

The results suggest monitoring binding kinetics based on fluorescently labeled bisphosphonates represents a highly sensitive, site-specific method for monitoring changes in bone mineral deposition with the potential for translation into human applications in osteoporosis and bone metastatic processes and their treatment