OSTEOCYTE-DERIVED RANKL IS A CRITICAL MEDIATOR OF THE INCREASED BONE RESORPTION CAUSED BY DIETARY CALCIUM DEFICIENCY

Bone. 2014 Sep;66:146-54

These results demonstrate that RANKL produced by osteocytes contributes to the increased bone resorption and the bone loss caused by secondary hyperparathyroidism, strengthening the evidence that osteocytes are an important target cell for hormonal control of bone remodeling

Autor: Xiong J, Piemontese M, Thostenson JD, Weinstein RS, Manolagas SC, O’Brien CA.
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