Vitamin D3 and calcidiol are not equipotent
Calcidiol is faster and 3-6 times more potent to obtain serum levels of 25(OH)D in the medium to long term.
Premios Fundación Lilly de Investigación Biomédica Preclínica y Clínica 2016
La Fundación Lilly, en desarrollo de sus objetivos estatutarios y dentro del programa de Apoyo a la Investigación BIOMÉDICA, convoca los Premios Fundación Lilly de Investigación Biomédica Preclínica y Clínica 2016, para investigadores que hayan … Leer más
FGF23-regulated production of Fetuin-A (AHSG) in osteocytes
Bone. 2016 Feb;83:35-47. doi: 10.1016/j.bone.2015.10.008. Epub 2015 Oct 23. Our data not only confirm that AHSG is produced in bone, mainly in osteocytes, but show for the first time that its production is modulated by … Leer más
Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline: A Randomized Clinical Trial
JAMA Intern Med. 2016 Feb 1;176(2):175-83. doi: 10.1001/jamainternmed.2015.7148. Although higher monthly doses of vitamin D were effective in reaching a threshold of at least 30 ng/mL of 25-hydroxyvitamin D, they had no benefit on lower … Leer más
Relationship between spinal osteoarthritis and vertebral fractures in men older than 50 years: data from the Camargo Cohort Study
Our results suggest a positive relationship between radiologic osteoarthritic changes at the thoracic spine and prevalent vertebral fractures in men more than 50 years of age. Osteoarthritis may act as a local risk factor, in … Leer más
Medication-related osteonecrosis of the jaw associated with bisphosphonates and denosumab in osteoporosis
Most of our cases were in the early stages of MRONJ, and the success rate after conservative treatment was high.
Role of Periostin in Adhesion and Migration of Bone Remodeling Cells
Role of Periostin in Adhesion and Migration of Bone Remodeling Cells
Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study
The introduction and/or expansion of orthogeriatric and FLS models of post-hip fracture care has a beneficial effect on subsequent mortality. No evidence for a reduction in second hip fracture rate was found.
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data
An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Within a strategy of a disease modifying approach to inflammatory disease, short durations of moderate doses of … Leer más
The COL1A1 SP1 polymorphism is associated with lower bone mineral density in patients treated with valproic acid
In our study, the presence of the ‘s’ allele of the COL1A1 Sp1 polymorphism in individuals with epilepsy was related to lower bone BMD (lumbar and femoral). This relationship seemed to be further apparent in … Leer más
