Comparison of two different strategies of treatment with zoledronate in HIV-infected patients with low bone mineral density: single dose versus two doses in 2 years
The benefits for BMD of a single dose of zoledronate in 2 years may be comparable to those obtained with two doses of the drug after 96 weeks, although this study is insufficiently powered to … Leer más
Cerrada Convocatoria Becas Feiomm ASBMR 2015
FEIOMM convoca 5 BECAS para la presentación de trabajos científicos en ASBMR 2015 Annual Meeting (American Society for Bone and Mineral Research) que se celebrará en Seattle, Washington (USA) del 9 al 12 de octubre … Leer más
Convocatoria Becas Feiomm ASBMR 2015
FEIOMM convoca 5 BECAS para la presentación de trabajos científicos en ASBMR 2015 Annual Meeting (American Society for Bone and Mineral Research) que se celebrará en Seattle, Washington (USA) del 9 al 12 de octubre … Leer más
Bisphosphonates for the prevention of fractures in osteogenesis imperfecta: meta-analysis of placebo-controlled trials
J Bone Miner Res. 2015 May;30(5):929-33. doi: 10.1002/jbmr.2410. We conclude that the effects of bisphosphonates on fracture prevention in osteogenesis imperfecta are inconclusive. Adequately powered trials with a fracture endpoint are needed to further investigate … Leer más
The Effect of 6 versus 9 Years of Zoledronic Acid Treatment in Osteoporosis: A Randomized Second Extension to the HORIZON-Pivotal Fracture Trial (PFT)
J Bone Miner Res. 2015 May;30(5):934-44. doi: 10.1002/jbmr.2442. The results suggest almost all patients who have received six annual ZOL infusions can stop medication for up to 3 years with apparent maintenance of benefits. Autor: … Leer más
Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study
COSMOS provides evidence of the association of serum phosphorus, calcium and PTH and mortality, and suggests survival benefits of controlling chronic kidney disease-mineral and bone disorder biochemical parameters in CKD5D patients.
DLK1 regulates whole body glucose metabolism: A negative feedback regulation of the osteocalcin-insulin loop
Our data suggest that Glu-OCN-controlled production of Delta like-1 (DLK1) by pancreatic β cells acts as a negative feedback mechanism to counteract the stimulatory effects of insulin on osteoblast production of Glu-OCN, a potential mechanism … Leer más
Inappropriate prescribing to the oldest old patients admitted to hospital: prevalence, most frequently used medicines, and associated factors
Prescribed medicines and potentially inappropriate medicines (PIM) and potentially prescribing omissions (PPO) prevalence were high among patients 85 years and over. Benzodiazepine use in those who are prone to falls and omission of calcium and … Leer más
Disability-adjusted-life-years losses in postmenopausal women with osteoporosis: a burden of illness study
DALY losses were considerable amongst postmenopausal women with osteoporosis. Not having a prior bone fracture, being older, using a SERM and having less osteoporotic risk factors were all linked to less DALY losses.
