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Calcif Tissue Int (2015) 96:500–509 DOI 10.1007/s00223-015-9980-x They have demonstrated that lumbar spine texture analysis using TBS is a risk factor for osteoporotic fracture and also for risk of death. The predictive ability of TBS … Leer más

J Bone Miner Res. 2015 Mar;30(3):488-97- Using different osteotropic human prostate cancer cell lines, the influence of WNT5A overexpression and knock-down on proliferation, migration, and apoptosis was assessed. In vitro, WNT5A overexpression induced prostate cancer … Leer más

J Bone Miner Res. 2015 Mar;30(3):436-48. doi: 10.1002/jbmr.2374. These findings suggest that osteocytic Cx43 channels play distinctive roles in the bone; hemichannels play a dominant role in regulating osteocyte survival, endocortical bone resorption, and periosteal … Leer más

J Clin Endocrinol Metab. 2015 Mar;100(3):1018-27. doi: 10.1210/jc.2014-3096. Epub 2014 Dec 11. Although the use of a LSBMD Z-score threshold as part of the definition of osteoporosis in a child with VF does not appear … Leer más

Higher serum uric acid levels in men older than 50 years are positively associated with QUS parameters. These data might suggest a better bone quality in men with elevated serum uric acid values.

At 7 years, the cumulative incidences of new vertebral fractures were significantly lower in the bazedoxifene (6.4%) and bazedoxifene 20 mg (7.6%) groups than in the placebo group (9.9%); the relative risk reductions were 36.5% … Leer más

Regardless of differences in health care delivery systems and medication reimbursement plans, the use of osteoporosis medications for the secondary prevention of osteoporotic fracture was low. Adherence to osteoporosis treatment was also suboptimal with the … Leer más

Clin Endocrinol Metab. 2015 Feb;100(2):475-82. doi: 10.1210/jc.2014-2047. The inverse association between lumbar spine TBS and insulin resistance may make it an indicator for determining skeletal deterioration in diabetic patients who have high BMD. Autor: Kim … Leer más

J Bone Miner Res. 2015 Feb;30(2):216-24. doi: 10.1002/jbmr.2351. These results support further study of blosozumab as a potential anabolic therapy for osteoporosis. Autor: ReckerRR,BensonCT,MatsumotoT,BologneseMA,RobinsDA,A J,ChiangAY,Hu L,Krege JH, Sowa H,Mitlak BH,M SL