J. Bone Miner Res 2014; 29: 935–943. DOI: 10.1002/jbmr.2092 Conclusions: These findings support further investigation of blosozumab as a potential anabolic therapy for osteoporosis. Autor: McColm J, Hu L, Womack T, Cai Tang C, Chiang … Leer más
Los Premios BIAL apoyan y premian la investigación médica con 340.000 euros.• Uno de los objetivos principales del Premio BIAL, que cumple su 30 aniversario, es aumentar el número de candidaturas internacionales • El Premio … Leer más
Nature. 2014 Feb 13;506(7487):240-4. doi: 10.1038/nature12883. Epub 2014 Jan 15 These findings demonstrate that genetic alterations in osteoblasts can induce acute myeloid leukaemia, identify molecular signals leading to this transformation and suggest a potential novel … Leer más
In conclusion, our study does not support the hypothesis that calcium supplementation increases either carotid artery intimal medial thickness or carotid atherosclerosis. In addition, calcium supplementation and high total calcium intake may indeed reduce carotid … Leer más
La Fundación Lilly, en desarrollo de sus objetivos estatutarios y dentro del programa de Apoyo a la Investigación, convoca los Premios Fundación Lilly de Investigación Biomédica Preclínica y Clínica 2014, para investigadores que hayan contribuido … Leer más
In conclusion, despite the huge impact of osteoporosis worldwide, our knowledge of bone genetics and biology remains remarkably incomplete. Our findings and models provide compelling genetic evidence of a novel molecular network regulating adult skeletal … Leer más
The trabecular bone score (TBS) is a gray‐level textural metric that can be extracted from the two‐dimensional lumbar spine dual‐energy X‐ray absorptiometry (DXA) image. TBS is related to bone microarchitecture and provides skeletal information that … Leer más
J Clin Invest. 2014 Apr 1;124(4):1-13. doi: 10.1172/JCI72323. Epub 2014 Mar 18. Together, these results underscore the involvement of bone, among other tissues, in the disruption of whole-body glucose homeostasis resulting from a HFD and … Leer más
The results of this nested case–control study in the CPRD indicate no evidence for a higher risk of MI or cardiovascular death associated with the use of strontium ranelate in women treated for osteoporosis compared … Leer más
Osteoporos Int (2014) 25:1267–1274. DOI 10.1007/s00198-013-2586-0. Conclusions This study supports other international studies by showing changes in the incidence of hip fractures after age population adjustment, which denotes a decrease in the younger age groups … Leer más
