tandard and multifactorial interventions are very effective in reducing unnecessary treatments with bisphosphonates. The multifactorial intervention is more effective than the standard one, although more complex to implement
The combination of interventions may be effective to enhance trabecular bone microarchitecture and BMD, and has a partial impact on cortical bone in obese rats. Nevertheless, they do not induce any alteration on the bone … Leer más
AI therapy induces significant decreases in TBS, comparable to BMD loss. BP-treated patients maintained TBS values, whereas BMD increased. AI treatment leads to deterioration of bone microarchitecture, which seems to be attenuated by BP therapy.
J Bone Miner Res. 2016 Sep;31(9):1753-9. doi: 10.1002/jbmr.2849. Epub 2016 Apr 30. Parental Hip Fracture (HF) increased the risk for offspring Major Osteoporotic Fracture (MOF) and HF but not when parental HF occurred after age … Leer más
J Clin Endocrinol Metab. 2016 Sep;101(9):3297-305. doi: 10.1210/jc.2016-1366. Epub 2016 Jun 13. CONCLUSIONS: Midlife women with high fasting plasma TG had an increased risk of incident nontraumatic fracture. Secondary Abstract: Midlife women with fasting plasma … Leer más
J Bone Miner Res. 2016 Sep;31(9):1638-46. doi: 10.1002/jbmr.2887. Epub 2016 Jul 26. Despite these challenges, an understanding of the mechanisms by which the gut microbiome affects bone has the potential to provide insights into the … Leer más
J Bone Miner Res. 2016 Sep;31(9):1767-73. doi: 10.1002/jbmr.2847. Epub 2016 Apr 25. In conclusion, serum PINP is potentially useful in monitoring response to zoledronic acid. Further research is needed to evaluate the effects of monitoring … Leer más
JAMA. 2016 Aug 16;316(7):722-33. doi: 10.1001/jama.2016.11136. Among postmenopausal women with osteoporosis, the use of subcutaneous abaloparatide, compared with placebo, reduced the risk of new vertebral and nonvertebral fractures over 18 months. Further research is needed … Leer más
J Clin Endocrinol Metab. 2016 Aug;101(8):3105-13. doi: 10.1210/jc.2016-1559. Epub 2016 May 26. Sun exposure levels failed to provide adequate vitamin D, with approximately one-quarter of adolescents insufficient even at summer peak. Seasonal vitamin D deficiency … Leer más
J Clin Endocrinol Metab. 2016 Aug;101(8):3163-70. doi: 10.1210/jc.2016-1801. Epub 2016 Jun 6 In postmenopausal women with osteoporosis previously treated with oral bisphosphonates, denosumab was associated with greater BMD increases at all measured skeletal sites and … Leer más
