J Intern Med. 2016 Oct;280(4):350-8. doi: 10.1111/joim.12520. Epub 2016 Jun 6. DOI: 10.1111/joim.12520 PMID: 27272530 [PubMed – in process] The success of antiretroviral therapy in treating HIV infection has greatly prolonged life expectancy in affected … Leer más
Lancet. 2016 Oct 1;388(10052):1408-1416. doi: 10.1016/S0140-6736(16)31341-1. PMID: 27544377 Vertebroplasty is superior to placebo intervention for pain reduction in patients with acute osteoporotic spinal fractures of less than 6 weeks’ in duration. These findings will allow … Leer más
Bone. 2016 Oct;91:30-8. doi: 10.1016/j.bone.2016.06.013. Epub 2016 Jun 25. Review. This review (i) summarizes the roles of VEGF at different stages of bone repair, including the phases of inflammation, endochondral ossification, intramembranous ossification during callus … Leer más
Bone. 2016 Oct;91:122-9. doi: 10.1016/j.bone.2016.07.019. Epub 2016 Jul 25. Due to the lack of efficacy in preventing fractures, the development of the orally formulated calcitonin was terminated despite the promising results in earlier studies. Autor: … Leer más
J Clin Endocrinol Metab. 2016 Nov;101(11):4489-4496. Diabetes is a FRAX-independent risk factor for MOF only in women with a long duration of diabetes, but diabetes increases hip fracture risk, regardless of duration. Those with diabetes … Leer más
tandard and multifactorial interventions are very effective in reducing unnecessary treatments with bisphosphonates. The multifactorial intervention is more effective than the standard one, although more complex to implement
The combination of interventions may be effective to enhance trabecular bone microarchitecture and BMD, and has a partial impact on cortical bone in obese rats. Nevertheless, they do not induce any alteration on the bone … Leer más
AI therapy induces significant decreases in TBS, comparable to BMD loss. BP-treated patients maintained TBS values, whereas BMD increased. AI treatment leads to deterioration of bone microarchitecture, which seems to be attenuated by BP therapy.
On the basis of the aforementioned observations, these hydrogels are very attractive for bone tissue engineering.
Our data indicates an altered bone remodelling rate in the Type 2 diabetes mellitus group, which may, at least partially, explain the reduced bone strength and increased incidence of non-traumatic fractures in diabetic patients
