Bone. 2016 Oct;91:122-9. doi: 10.1016/j.bone.2016.07.019. Epub 2016 Jul 25. Due to the lack of efficacy in preventing fractures, the development of the orally formulated calcitonin was terminated despite the promising results in earlier studies. Autor: … Leer más
J Clin Endocrinol Metab. 2016 Nov;101(11):4489-4496. Diabetes is a FRAX-independent risk factor for MOF only in women with a long duration of diabetes, but diabetes increases hip fracture risk, regardless of duration. Those with diabetes … Leer más
The combination of interventions may be effective to enhance trabecular bone microarchitecture and BMD, and has a partial impact on cortical bone in obese rats. Nevertheless, they do not induce any alteration on the bone … Leer más
AI therapy induces significant decreases in TBS, comparable to BMD loss. BP-treated patients maintained TBS values, whereas BMD increased. AI treatment leads to deterioration of bone microarchitecture, which seems to be attenuated by BP therapy.
On the basis of the aforementioned observations, these hydrogels are very attractive for bone tissue engineering.
Our data indicates an altered bone remodelling rate in the Type 2 diabetes mellitus group, which may, at least partially, explain the reduced bone strength and increased incidence of non-traumatic fractures in diabetic patients
tandard and multifactorial interventions are very effective in reducing unnecessary treatments with bisphosphonates. The multifactorial intervention is more effective than the standard one, although more complex to implement
J Bone Miner Res. 2016 Sep;31(9):1753-9. doi: 10.1002/jbmr.2849. Epub 2016 Apr 30. Parental Hip Fracture (HF) increased the risk for offspring Major Osteoporotic Fracture (MOF) and HF but not when parental HF occurred after age … Leer más
J Clin Endocrinol Metab. 2016 Sep;101(9):3297-305. doi: 10.1210/jc.2016-1366. Epub 2016 Jun 13. CONCLUSIONS: Midlife women with high fasting plasma TG had an increased risk of incident nontraumatic fracture. Secondary Abstract: Midlife women with fasting plasma … Leer más
J Bone Miner Res. 2016 Sep;31(9):1638-46. doi: 10.1002/jbmr.2887. Epub 2016 Jul 26. Despite these challenges, an understanding of the mechanisms by which the gut microbiome affects bone has the potential to provide insights into the … Leer más
