Longer Duration of Diabetes Strongly Impacts Fracture Risk Assessment: The Manitoba BMD Cohort

J Clin Endocrinol Metab. 2016 Nov;101(11):4489-4496.

Diabetes is a FRAX-independent risk factor for MOF only in women with a long duration of diabetes, but diabetes increases hip fracture risk, regardless of duration. Those with diabetes longer than 10 years are at particularly high risk of fracture, and this elevated risk is currently underestimated by FRAX.

In a large study we found it was long duration of diabetes that was more important than the diagnosis itself in predicting fracture risk, and that FRAX under-estimates risk in women with diabetes.

Autor: Sumit R. Majumdar, William D. Leslie, Lisa M. Lix, Suzanne N. Morin, Helena Johansson,Anders Oden, Eugene V. McCloskey and John A. Kanis

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