Conjugated estrogens/bazedoxifene improved vasomotor symptoms, genitourinary syndrome of menopause, and BMD in Latin American women, with efficacy/safety similar to the global population.
J Bone Miner Res. 2016; 31(8):1527-35. doi: 10.1002/jbmr.2825. Epub 2016 Mar 30. TPTD stimulated new bone formation, producing a mineralized bone matrix that remained relatively heterogeneous with a stable mean mineral content. ZOL slowed bone … Leer más
JAMA Intern Med. 2016 Mar 28. doi: 10.1001/jamainternmed.2016.0482. [Epub ahead of print] Higher adherence to a Mediterranean diet is associated with a lower risk for hip fractures. These results support that a healthy dietary pattern … Leer más
Our data confirm a clinically relevant bone loss associated with aromatase inhibitors (AI) therapy amongst non-users of preventative bisphosphonates. We further report on the importance of BMD monitoring as well as calcium and 25(OH)vitD supplementation … Leer más
Bone. 2016 Mar;84:57-68. doi: 10.1016/j.bone.2015.12.016. Epub 2015 Dec 23. Review. Given the polygenic nature of skeletal diseases like osteoporosis and osteoarthritis, validating the function of additional miRNA-associated SNPs has the potential to enhance our understanding … Leer más
There was no significant difference between suffering a second hip fracture and following osteoporosis treatment, using psychotropic drugs or being institutionalised.
Bone. 2016 Mar;84:279-88. doi: 10.1016/j.bone.2015.12.006. Epub 2015 Dec 17 These data suggest demineralization can occur from within bone through the canalicular system, and that peri-canalicular demineralization occurs not uniformly but directed by individual osteocytes. Blockade … Leer más
Unintentional weight loss at baseline was associated with a significantly increased risk of fracture of the clavicle, wrist, spine, rib, hip, and pelvis for up to 5 years following weight loss. This increase is seen … Leer más
Osteoporos Int. 2016 Mar;27(3):849-52. doi: 10.1007/s00198-015-3453-y. Epub 2015 Dec 14. No abstract available. Clinicians need to rethink the assumption that a patient who has taken an oral bisphosphonate for 5 years or an intravenous therapy … Leer más
Calcidiol is faster and 3-6 times more potent to obtain serum levels of 25(OH)D in the medium to long term.
