J Clin Endocrinol Metab. 2016 Apr;101(4):1414-21. doi: 10.1210/jc.2015-4017. Epub 2016 Feb 10. In this large, prospective, observational cohort study of postmenopausal women in the WHI, Cox proportional hazard regression models showed that sodium intake at … Leer más
Bone. 2016 Mar;84:279-88. doi: 10.1016/j.bone.2015.12.006. Epub 2015 Dec 17 These data suggest demineralization can occur from within bone through the canalicular system, and that peri-canalicular demineralization occurs not uniformly but directed by individual osteocytes. Blockade … Leer más
Unintentional weight loss at baseline was associated with a significantly increased risk of fracture of the clavicle, wrist, spine, rib, hip, and pelvis for up to 5 years following weight loss. This increase is seen … Leer más
Osteoporos Int. 2016 Mar;27(3):849-52. doi: 10.1007/s00198-015-3453-y. Epub 2015 Dec 14. No abstract available. Clinicians need to rethink the assumption that a patient who has taken an oral bisphosphonate for 5 years or an intravenous therapy … Leer más
Calcidiol is faster and 3-6 times more potent to obtain serum levels of 25(OH)D in the medium to long term.
Osteoporos Int. 2016 Mar;27(3):861-71. doi: 10.1007/s00198-015-3331-7. Epub 2015 Sep 29 Further clinical studies with these medications are needed to fully understand their effects on fracture healing in order to simultaneously treat fragility fractures and underlying … Leer más
Chronic abnormal phosphaturia explains, at least in part, progressive bone loss during TDF therapy. These data suggest that tubular dysfunction leads to an altered equilibrium between phosphatemia, phosphaturia and bone as mechanism of progressive BMD … Leer más
J Bone Miner R 2016 Mar;31(3):491-7. doi: 10.1002/jbmr.2767. Epub 2016 Jan 8 We conclude that in contrast to ordinary subtrochanteric and femoral shaft fractures, atypical femoral fractures are not associated with excess mortalityes. Autor: Kharazmi … Leer más
J Bone Miner Res. 2016; 31(8):1527-35. doi: 10.1002/jbmr.2825. Epub 2016 Mar 30. TPTD stimulated new bone formation, producing a mineralized bone matrix that remained relatively heterogeneous with a stable mean mineral content. ZOL slowed bone … Leer más
JAMA Intern Med. 2016 Mar 28. doi: 10.1001/jamainternmed.2016.0482. [Epub ahead of print] Higher adherence to a Mediterranean diet is associated with a lower risk for hip fractures. These results support that a healthy dietary pattern … Leer más
