Vitamin D insufficiency is very common among Spanish community-dwelling adult subjects. A threshold of serum 25(OH)D around 30 ng/ml would be necessary for the prevention of secondary hyperparathyroidism and hip bone loss in our population, … Leer más
In this review, we discuss the current concepts about the cellular and molecular mechanisms whereby PTHrP may induce anabolic actions in bone. Pre-clinical studies and clinical data using N-terminal PTHrP analogs are also summarized, pointing … Leer más
Calcif Tissue Int. 2015 Sep;97(3):199-200. doi: 10.1007/s00223-015-0012-7. Epub 2015 May 13. Autor: Burr DB, Allen MR.
Osteoporos Int. 2015 Sep;26(9):2223-41. doi: 10.1007/s00198-015-3149-3. Epub 2015 May 5. In this review, we summarize our current understanding of the pathophysiology of fragility fractures that occur for the first time during pregnancy and lactation, and … Leer más
PLoS One. 2015 Sep 8;10(9):e0136968. doi: 10.1371/journal.pone.0136968. eCollection 2015. Frailty and pre-frailty, in Taiwan, was closely associated with recent falls, history of hip fractures and osteoporosis among community-dwelling people 50 years of age and older. … Leer más
Osteoporos Int. 2015 Sep;26(9):2257-63. doi: 10.1007/s00198-015-3117-y. Epub 2015 Apr 10. The available data also showed that patients attending the FLSs were evaluated, treated and followed in high compliancy with the IOF standards. Some standards are … Leer más
Most of the 13 tools are feasible in clinical practice. FRAX has the largest number of externally validated and independent studies. The overall accuracy of the different tools is satisfactory (>0.70), with QFracture reaching 0.89 … Leer más
Osteoporos Int. 2015 Sep;26(9):2355-63. doi: 10.1007/s00198-015-3148-4. Epub 2015 May 6. Compared with placebo, bisphosphonates could decrease the risk of vertebral and non-vertebral fractures, reduce BSAP and CTX, and increase BMD in men with osteoporosis. Autor: … Leer más
The results of this pilot study suggest that these fractures are polygenic and are associated with the accumulation of changes in the coding regions of several genes.
Calcif Tissue Int. 2015 Aug;97(2):101-3. doi: 10.1007/s00223-015-0021-6. Epub 2015 Jun 13. Bisphosphonates are extensively used for treatment of children and adults with osteogenesis imperfecta. Over years, studies have reported the response of BP treatment in … Leer más
