. J Clin Endocrinol Metab. 2015 Jul;100(7):2784-2792. Epub 2015 May 8 Denosumab allows for supra-physiologic doses of calcitriol resulting in decreased parathyroid secretion and parathyroid hyperplasia. Supervised administration and weekly laboratory and clinical monitoring of … Leer más
After adjustment for confounders, high PINP levels (defined by the upper quartile) and low levels of 25(OH)D (lower quartile) remained significantly associated to frailty [OR for PINP: 2.19; OR for 25(OH)D: 1.65]. Women with both … Leer más
Although the results of cross-sectional studies were inconsistent, the results of randomized controlled trials showed that exercise has the potential to improve bone health under conditions of adequate calcium intake.
In this review we study the pathogenesis of bone changes in alcoholic liver disease and discuss potential therapies.
The evaluation of BMD at the lumbar spine and femur short-term after spinal cord injury (SCI) is a simple, effective method for predicting the development of osteoporosis during the first year after SCI. Our results … Leer más
Patients with higher body mass index and those receiving higher doses of glucocorticoids are at increased risk of having lower levels of 25(OH)D. In these patients, calcidiol supplementations are more effective than cholecalciferol to reach … Leer más
The genetic association of CYP11A1 gene with AIBL and its expression in bone tissue reveals a potential local function of this enzyme in bone metabolism regulation, offering a new vision of the steroidogenic ability of … Leer más
The aims of this review is to compile the basic characteristics of these drugs and outline the most important benefits and side effects and provide a clinical context as well as a research agenda to … Leer más
The benefits for BMD of a single dose of zoledronate in 2 years may be comparable to those obtained with two doses of the drug after 96 weeks, although this study is insufficiently powered to … Leer más
