Epidemiology of fractures in type 2 diabetes
Bone. 2016 Jan;82:2-8. doi: 10.1016/j.bone.2015.05.032. Epub 2015 May 29. Review. This article is part of a Special Issue entitled “Bone and diabetes” Autor: Schwartz AV
Implications of exercise-induced adipo-myokines in bone metabolism
The beneficial effects of exercise on bone metabolism depends on the intermittent exposure to myokines which, instead, act as inflammatory/pro-resorptive mediators when chronically elevated; on the other hand, the reduction in the circulating levels of … Leer más
Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis
A deeper knowledge of the mechanisms involved in chondrocyte aging could identify potential targets for the treatment of OA, a prevalent and therapeutic-orphan disease.
New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr-/- mice
GQ-177, a new thiazolidinedione, acts as a partial PPARγ agonist that improves obesity-associated insulin resistance and dyslipidemia with atheroprotective effects in LDLr-/- mice.
Efficacy and safety of alendronic acid in the treatment of osteoporosis in children
Alendronate increased bone mineral density and was well tolerated in all patients, therefore it could be considered as a therapeutic option in the treatment of osteoporosis in children.
Convocatoria BECAS FEIOMM INVESTIGACIÓN 2016
La Fundación Española de Investigación Ósea y del Metabolismo Mineral (FEIOMM), convoca 6 BECAS de 6.000€ cada una para promocionar la investigación básica, clínica y traslacional en el campo del metabolismo mineral y óseo
Trabecular bone score in patients with liver transplants after one year of risedronate treatment
No significant effect in TBS was observed in liver transplant patients treated with RIS or calcium and vitamin D3 after 1 year of follow-up. In these patients the clinical usefulness of this new tool should … Leer más
Influence of age on rat bone-marrow mesenchymal stem cells potential
Taking together these results indicate for the first time that mesenchymal stem cells have significant differences in their proliferative, pluripotency and metabolism profiles and those differences are age depending.
MiRNA profiling of whole trabecular bone: identification of osteoporosis-related changes in MiRNAs in human hip bones
We identified two osteoblast miRNAs over-expressed in osteoporotic fractures, which opens novel prospects for research and therapy.
The role of CD40 and CD40L in bone mineral density and in osteoporosis risk: A genetic and functional study
Our results suggest that the CD40/CD40L system plays a role in regulating BMD. Effectively, our data suggest that a decreased production of OPG could be the cause of the lower BMD observed in TT women … Leer más
