Bone density, microarchitecture, and material strength in chronic kidney disease patients at the time of kidney transplantation.

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Bone health is assessed by bone mineral density (BMD). Other techniques such as trabecular bone score and microindentation could improve the risk of fracture’s estimation. Our chronic kidney disease (CKD) patients presented worse bone health (density, microarchitecture, mechanical properties) than controls. More than BMD  should be done to evaluate patients at risk of fracture. CONCLUSIONS: ESRD patients undergoing transplant surgery have damaged bone health parameters (density, microarchitecture, and mechanical properties) despite acceptably controlled hyperparathyroidism. Detecting these abnormalities may assist in identifying patients at high risk of post-transplantation fractures.

Osteoporos Int. 2017 May 11. doi: 10.1007/s00198-017-4065-5.

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Pérez-Sáez MJ, Herrera S, Prieto-Alhambra D, Vilaplana L, Nogués X, Vera M, Redondo-Pachón D, Mir M, Güerri R, Crespo M, Díez-Pérez A, Pascual J

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Lilly
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Grupo Italfármaco
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Kyowa Kirin
Amgen
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