J Bone Miner Res. 2016 Feb;31(2):261-9. doi: 10.1002/jbmr.2765. Review.

This perspective discusses evidence to date on the role of the microbiome and the highly prevalent age-related disorders of osteoporosis, osteoarthritis, gout, rheumatoid arthritis, sarcopenia, and frailty. It also reviews data on the effects of probiotics and prebiotic interventions in animal and human models. Despite suggestive findings, research to date is not conclusive, and we identify priorities for research to substantiate and translate findings.

Autor: Steves CJ, Bird S, Williams FM, Spector TD.

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