Although prophylaxis of glucocorticoid-induced osteoporosis in patients with PMR has increased in the recent years, many patients do not receive prophylaxis with bisphosphonate during the first visit.
Osteoporos Int (2014) 25:2347–2357 To revisit the question posed in the title of this review, is vitamin D a tonic for bone and soft tissue? Probably not, but levels of <25–40 nmol/L do have significant … Leer más
Bone. 2015 May 24;79:37-42. doi: 10.1016/j.bone.2015.05.022. [Epub ahead of print] The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. Microvesicles (MVs) have received a good deal of attention and … Leer más
JAMA Intern Med. 2014 May 5. doi: 10.1001/jamainternmed.2014.1232. [Epub ahead of print] Among postmenopausal women who discontinue alendronate therapy after 4 to 5 years, age and hip BMD at discontinuation predict clinical fractures during the … Leer más
JAMA Intern Med. 2014 May 5. doi: 10.1001/jamainternmed.2014.162. [Epub ahead of print] The clinical utility of medication monitoring has been a controversial issue in osteoporosis management. In the 1998 and 20012 coverage rules commonly called … Leer más
Bone 2014; 62:22-28 Notch1 and Notch2 inactivation increased porosity and reduced thickness of cortical bone. These effects were modest and more evident in 3 and 6 month old female than in male mice of the same … Leer más
MrOs Sweden. Osteoporos Int 2014;25:1831-1836 Serum adiponectin is a risk factor for fracture. Nevertheless, the predictive value attenuates with time so that its use for the risk assessment in the long term is questionable. This … Leer más
JAMA. 2014 May 28;311(20):2083-91. doi: 10.1001/jama.2014.5052. Vitamin D3 did not reduce the rate of first treatment failure or exacerbation in adults with persistent asthma and vitamin D insufficiency. These findings do not support a strategy … Leer más
Bone-tissue engineering is a therapeutic target in the field of dental implant and orthopedic surgery. It is therefore essential to find a microenvironment that enhances the growth and differentiation of osteoblasts both from mesenchymal stem … Leer más
Gene candidate and genome-wide association studies have revealed tens of loci of susceptibility for osteoporosis. The results underscore the significance of the LRP5 gene in bone metabolism and emphasize the significance of the replication of … Leer más
