Effects of antidepressants on postmenopausal bone loss – A 5-year longitudinal study from the OSTPRE cohort

Bone. 2016 Aug;89:25-31. doi: 10.1016/j.bone.2016.05.003. Epub 2016 May 11.

In conclusion, the use of SSRIs seems to accelerate postmenopausal bone loss in a dose-response manner. Associations between TCA and other antidepressant use and bone loss may also exist. Thus, the possibility of increased risk of osteoporosis should be considered when prescribing antidepressants for postmenopausal women.

Autor: Rauma PH, Honkanen RJ, Williams LJ, Tuppurainen MT, Kröger HP, Koivumaa-Honkanen H.
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