Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations

J Clin Endocrinol Metab. 2016 May;101(5):2226-34. doi: 10.1210/jc.2016-1104. Epub 2016 Mar 23.

Previously reported racial differences in DBP concentration are likely from monoclonal assay bias, as there was no racial difference in DBP concentration by other methods. This confirms the poor vitamin D status of many African-Americans and the utility of total 25OHD in assessing vitamin D in the general population.

Autor: Nielson CM,Jones KS,Chun RF,Jacobs JM,Wang Y,Hewison M,Adams JS,Swanson CM,Lee C,anderschueren D,Pauwels S,Prentice A,Smith RD,Shi T,Gao Y,Schepmoes AA,Zmuda JM,Lapidus J,Cauley JA,Bouillon R,Schoenmakers I,Orwoll ES;OFMen (MrOS) Research G.
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