J Am Soc Nephrol. 2016 Dec 7
Parathyroid hormone (PTH) is a primary calcium regulatory hormone. Elevated serum PTH concentrations in primary and secondary hyperparathyroidism have been associated with bone disease, hypertension, and in some studies, cardiovascular mortality. Genetic causes of variation in circulating PTH concentrations are incompletely understood. This study performed a genome-wide association study of serum PTH concentrations among 29,155 participants of European ancestry from 13 cohort studies.
Autor: RobinsonCC,LutseyPL,KleberME,NielsonCM,MitchellBDBisJC,EnyKMPortasL,ErikssonJ,LorentznM,KollerDLMilaneschiY,TeumerA,PilzS,NethanderM,SelvinE,TanGW,WengLC,WongHS,LaiD,PeacockM,HannemannA,VölkerU,HomuthG,NaukM,MurgiaF,PatteeJW,OrwollE,ZmudaJM,RianchoJA