Literature review: The effects of teriparatide therapy at the hip in patients with osteoporosis

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Bone 67; 246–256. doi: 10.1016/j.bone.2014.07.014. Epub 2014 Jul 15

Studies using dual-energy X-ray absorptiometry and quantitative computed tomography for longitudinal assessment of changes at the hip have consistently shown increases in areal and volumetric bone mineral density, cortical thickness, and finite element-estimated hip strength in patients treated with teriparatide. Finally, in clinical fracture-outcome trials, treatment with teriparatide has been shown to reduce the risk of nonvertebral fracture, a composite endpoint that includes hip fracture. Taken together, this body of evidence suggests that teriparatide positively affects the hip in patients with osteoporosis.

Autor: Eriksen EF, Keaveny TM, Gallagher ER, Krege JH.
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